Senior Molecular Biologist

SLS Services Limited; City Of London; Sur place; GBP 60 000 - 90 000; Plein temps

Résumé du poste

A biotechnology company in the City of London is seeking a Senior Molecular Biologist to contribute to advancements in the gene therapy industry. The ideal candidate will have extensive experience in plasmid construction and DNA manufacturing. Responsibilities include genetically engineering plasmid DNA for synthetic DNA products and ensuring work is conducted in GMP environments. A strong background in various cloning methods is essential for this role.

Qualifications

• 2+ years of industry experience in plasmid construction.
• 1+ year of experience in GMP environments.
• Demonstrable experience in designing strategies for constructing complex plasmids.
• Demonstrable experience in designing strategies and experiments for constructing complex plasmids.
• Experience in DNA purification kits at various scales, using both commercial kits and self-packed hardware.
• Client-facing experience.
• Proven ability to work under pressure and meet tight deadlines.
• Proficiency in cloning methods such as PCR, Golden Gate, and Gibson Assembly.

Responsabilités

• Genetically engineer plasmid DNA starting material for synthetic DNA products.
• Contribute to advancements in the gene therapy industry.
• Work under pressure to meet tight deadlines.
• Collaborate with clients and internal teams to deliver results under tight deadlines.

Connaissances

Plasmid construction

GMP experience

Theoretical sequence maps

Primer design

Bacterial transformation

Amplification techniques

Complex plasmid construction

DNA purification kits

Client-facing experience

Cloning methods (PCR, Golden Gate, Gibson Assembly)

Description du poste

A new permanent opportunity for a Senior Molecular Biologist has recently become available. This is an exciting role for an experienced scientist eager to contribute to advancements in the gene therapy industry by working on synthetic DNA manufacturing.

This position is ideal for someone with a strong background in molecular biology, particularly in DNA manufacturing and genetic engineering. You will be responsible for genetically engineering plasmid DNA starting material for synthetic DNA products, contributing to a rapidly growing field.

Key Skills and Experience:

• 2+ years of industry experience in plasmid construction
• 1+ year of experience in GMP environments
• Expertise in creating theoretical sequence maps, primer design, bacterial transformation, and amplification
• Demonstrable experience in designing strategies and experiments for constructing complex plasmids
• Experience in DNA purification kits at various scales, using both commercial kits and self-packed hardware
• Client-facing experience
• Proven ability to work under pressure and meet tight deadlines
• Proficiency in cloning methods such as PCR, Golden Gate, and Gibson Assembly

Strongly Desired:

• Experience in a CDMO environment
• Experience using 3+ cloning methods for a single plasmid construct

Further details will be provided upon application.