Lead Hardware Engineer, DNA Synthesis Instrument (Hybrid)

Lab Automation Forums (labautomation.io); Greater London; Hybride; GBP 90 000 - 130 000; Plein temps

Résumé du poste

AmpliSynth, a London-based biotechnology startup, is building the next generation of DNA synthesis instrumentation. We seek the first engineering hire to lead design, prototyping, validation, and delivery, collaborating with the CEO and CSO to translate experiments into robust hardware and software.

Based in London with hybrid work options, you will own instrument architecture, testing, and integration with liquid handling systems, balancing performance with development speed and cost.

Qualifications

• Degree in Mechanical Engineering, Robotics, Electrical Engineering, Physics or related discipline.
• EngD or equivalent experience is beneficial.
• Experience developing complex hardware products from concept to deployment.
• Hands-on experience with electromechanical systems, automation and lab instrumentation.
• Ability to design, build, test and troubleshoot systems independently.
• Experience with embedded systems and programming environments (Python, C++, Rust).
• Comfortable in a fast‑moving early‑stage startup with evolving priorities.
• Strong communication skills and ability to work with scientists.

Responsabilités

• Lead design and hardware implementation of systems for biochemical workflows.
• Translate biological workflows into hardware/software requirements.
• Design and prototype subsystems including thermal control, liquid handling, and motion systems.
• Integrate prototypes with liquid handlers (Opentrons first, then Hamilton/Tecan/Beckman).
• Collaborate with founders to develop experimental methods and validate instrument performance.
• Manage external suppliers, manufacturers and contractors as needed.
• Improve SynthBox quality and user experience with design partners.
• Support pilot deployments and handover of early systems.
• Build and lead the future engineering function as the company grows.

Connaissances

Python

C++

Rust

Embedded systems

Control software

Hardware prototyping

Automation

Robotics

Software/hardware integration

Strong communication

Formation

Bachelor’s or higher degree in Mechanical Engineering, Robotics, Electrical Engineering, Physics or related discipline

EngD or equivalent

Outils

Opentrons

Hamilton

Tecan

Beckman

Description du poste

AmpliSynth, a London-based biotechnology startup, is building the next generation of DNA synthesis instrumentation. We seek the first engineering hire to lead design, prototyping, validation, and delivery, collaborating with the CEO and CSO to translate experiments into robust hardware and software.

Based in London with hybrid work options, you will own instrument architecture, testing, and integration with liquid handling systems, balancing performance with development speed and cost.