Senior Scientist, Single-Cell Mass Spectrometry & Proteomics

Ellison Institute of Technology Oxford; Oxford; On-site; GBP 90,000 - 130,000; Full time

Benefits offered by this job

Travel Allowance & Annual Bonus

Pension - Employer contribution 7.5%

Life Assurance

Income Protection

Private Medical Insurance for you and/

Employee discounts

Electric car scheme

Nursery Salary Sacrifice scheme

Cycle to Work Scheme

Family Planning

Neurodiversity support including adv &

Coaching & Therapy services

Job summary

The Ellison Institute of Technology (EIT) in Oxford hosts the Generative Biology Institute (GBI) and seeks a Scientist/Senior Scientist with expertise in single-cell mass spectrometry to build and refine MS workflows. You will work with multiple research groups and tech hubs to deliver robust, scalable analytical methods across health, agriculture, and AI-enabled biology initiatives.

The role emphasizes developing new MS methods, troubleshooting complex workflows, and translating advanced MS

Qualifications

• PhD or equivalent in analytical chemistry, mass spectrometry, proteomics, metabolomics or a related field.
• Experience in LC-MS proteomics/metabolomics including sample prep, method development, data acquisition and QC.
• Strong knowledge of low-input or single-cell analytical workflows including single-cell proteomics/metabolomics.
• Proficiency with MS data analysis software such as Spectronaut, DIA-NN, MaxQuant, Proteome Discoverer, FragPipe, MS-DIAL or Skyline.
• Excellent communication and collaboration across multidisciplinary teams.

Responsibilities

• Develop, implement and optimise LC-MS-based workflows for low-input and single-cell proteomics/metabolomics.
• Support researchers in design, execution, analysis and interpretation of MS experiments, including sample prep and data interpretation.
• Develop SOPs, training material and user-facing guidance for single-cell and low-input MS workflows.
• Contribute to MS data analysis with bioinformatics, scientific computing and AI/ML teams.
• Assist in manuscript preparation, internal reports and external presentations.
• Promote and represent EIT/GBI at scientific meetings and events.

Skills

Mass spectrometry proteomics/metabolom

Single-cell workflows

Bottom-up/top-down proteomics

MS data analysis software

Cross-disciplinary communication

Education

PhD or equivalent advanced degree

Job description

The Ellison Institute of Technology (EIT) in Oxford hosts the Generative Biology Institute (GBI) and seeks a Scientist/Senior Scientist with expertise in single-cell mass spectrometry to build and refine MS workflows. You will work with multiple research groups and tech hubs to deliver robust, scalable analytical methods across health, agriculture, and AI-enabled biology initiatives.

The role emphasizes developing new MS methods, troubleshooting complex workflows, and translating advanced MS