Senior Scientist, HT-Analytical Method Development

Evotec SE; Macclesfield; On-site; GBP 75,000 - 110,000; Full time

Benefits offered by this job

Pension scheme

25 days holiday

Private medical insurance

Private dental cover

Wellbeing support

Permanent health insurance

Discretionary bonus scheme

Training & development opportunities

Cycle-to-work scheme

Refer a friend scheme

Onsite facilities

Job summary

Evotec SE, via its Cyprotex unit, is recruiting for an Associate Principal Scientist, HT-Analytical Method Development to join the Analytical Sciences team based at Alderley Park. The role focuses on high-throughput LC-MS/LC-MS/MS method development for non-standard compounds across ADME projects, with emphasis on robust documentation and regulatory compliance.

You will lead projects, mentor junior staff, ensure quality, and contribute to ongoing development of analytical capabilities within a

Qualifications

• Minimum BSc in relevant scientific discipline covering chemistry.
• Extensive experience of developing robust bioanalytical methods using LC-MS workflows.
• Produce accurate documentation and report all method development activities with high quality and compliance.
• Highly motivated team player with dedication.
• Plan, schedule and carry out work for timely project completion.
• Experience with LC-MS/MS for pre-clinical small/large molecules.
• Experience with MassLynx Analyst/Sciex OS or related software.
• Broad knowledge of analytical support in drug discovery/development.
• Knowledge of DMPK/ADME assays in drug discovery.
• Ability to perform routine maintenance/troubleshooting on LC-MS/MS.

Responsibilities

• Plan and conduct method development projects using LC-MS or LC-MS/MS for diverse compounds.
• Perform fit-for-purpose method qualification studies for regulatory projects.
• Serve as senior contact for project communication.
• Collaborate with scientists across teams to understand method applications.
• Ensure all errors and results are reported and corrected promptly.
• Stay up-to-date with scientific advances and regulatory guidelines.
• Maintain clean and organized lab and documentation per SOPs.
• Evaluate future technologies for HT-Analytical Method Development.
• Influence direction and investment in analytical capabilities.

Skills

Bioanalytical methods

LC-MS workflows

Documentation & compliance

Team leadership

Project planning

LC-MS/MS experience

Mass spectrometry software

Drug discovery knowledge

Equipment maintenance

Education

Bachelor of Science in Chemistry

Tools

MassLynx

Analyst

Sciex OS

Job description

Evotec SE, via its Cyprotex unit, is recruiting for an Associate Principal Scientist, HT-Analytical Method Development to join the Analytical Sciences team based at Alderley Park. The role focuses on high-throughput LC-MS/LC-MS/MS method development for non-standard compounds across ADME projects, with emphasis on robust documentation and regulatory compliance.

You will lead projects, mentor junior staff, ensure quality, and contribute to ongoing development of analytical capabilities within a