Senior Scientist - Bioprocessing R&D

Revvity, Inc.; Cambourne; On-site; GBP 90,000 - 120,000; Full time

Job summary

Revvity, Inc. is seeking a Senior Scientist in Cambridge to advance CHOSOURCE expression technologies.

You will lead hands-on research, address expression challenges, and drive platform improvements while collaborating with a cross-functional team to translate findings into commercially relevant solutions. The role focuses on developing CHO-based systems for diverse biologics, mentoring junior scientists, and contributing to a culture of innovation and rigorous scientific inquiry within

Qualifications

• PhD in life sciences with 5+ years postdoc or industry in CHO biology.
• Deep CHO cell line development and clone screening experience.
• Hands-on gene editing in mammalian cells (targeted integration, knockout, knock-in).

Responsibilities

• Lead independent research projects to develop CHOSOURCE platform features for stable and transient expression.
• Identify and evaluate emerging technologies to enhance platform performance.
• Apply gene editing to engineer novel host cell lines with enhanced production characteristics.
• Collaborate with senior scientists for cross-functional problem solving and platform advancement.
• Maintain comprehensive laboratory documentation and SOPs.
• Present data at internal and external meetings; support IP and regulatory documentation as needed.

Skills

CHO cell line development

Gene editing

DoE (Design of Experiments)

Molecular biology techniques

Cloning (Gibson, Golden Gate)

qPCR / ddPCR

Education

Ph.D. in life sciences (molecular biology, biochemistry, cell biology or genetics)

Tools

Gibson assembly

Golden Gate assembly

qPCR systems

ddPCR systems

Job description

About Us

Revvity is a developer and provider of end-to-end solutions designed to help scientists, researchers, and clinicians solve the world’s greatest health challenges. We pair the enthusiasm of an industry disruptor with the experience of a longtime leader. Our team of 11,000+ colleagues from around the globe are vital to our success and the reason we’re able to push boundaries in pursuit of better human health.

Find your future at Revvity

Revvity's R&D Bioprocessing department pioneers advanced expression platforms that power the manufacturing of next-generation biotherapeutics. Our portfolio includes specialized mammalian host cell lines, our innovative transposon-based expression system for rapid identification of high-expressing clones, and gene editing capabilities that enable custom cell line engineering. These technologies support both protein-based therapeutics and viral vector production, addressing the evolving needs of the biopharma industry.

Job summary

Join Revvity's Bioprocessing R&D team as a Senior Scientist, where you will drive innovation in our CHOSOURCE Expression platform. This is a hands‑on, lab-based product development role focused on advancing CHO-based expression technologies for biotherapeutic production. You will tackle real-world expression challenges, from optimizing productivity to enabling successful expression of diverse biologics and translating your findings into commercial products that empower biopharma customers worldwide. As a senior member of the team, you will play a key role in shaping the scientific direction of the platform and contributing to a culture of innovation and continuous improvement.

Job Title

Senior Scientist - Bioprocessing R&D

Location(s)

Cambridge (UK)

Key responsibilities:

• Lead independent research projects to develop and validate new CHOSOURCE platform features for both stable and transient expression applications, from experimental design through execution, analysis, and troubleshooting
• Identify and evaluate emerging technologies and scientific trends relevant to CHO-based expression systems, proposing novel approaches to enhance platform performance and differentiation
• Apply gene editing technologies to engineer and develop novel host cell lines with enhanced production characteristics
• Collaborate with peer senior scientists to drive cross‑functional problem‑solving and advance platform capabilities
• Foster collaborative relationships within the team and across Revvity departments
• Maintain comprehensive laboratory documentation and develop standard operating procedures
• Present clear, concise data at both internal and external meetings
• Support IP generation and regulatory documentation as needed for product commercialization

Essential Competencies & Requirements:

• Ph.D. in life science (molecular biology, biochemistry, cell biology or genetics) with a minimum of 5 years of postdoctoral experience or industry experience in a relevant scientific field
• In-depth knowledge of CHO cell line development, including stable pool generation, single cell cloning, and clone screening
• Strong expertise in gene editing technologies with hands‑on experience in mammalian cell line engineering, including targeted integration, gene knockout, and knock‑in strategies
• Practical understanding of the challenges associated with expressing diverse biologics including difficult‑to‑express proteins and more complex biologics
• Advanced molecular biology skills, including expertise in diverse cloning methods (Gibson assembly, Golden Gate assembly), PCR, qPCR, and ddPCR
• Experience applying Design of Experiment (DoE) methodologies to experimental design
• Strong analytical mindset with ability to troubleshoot complex technical problems systematically
• Proven ability to work effectively in cross‑functional, fast‑paced environments
• Exceptional team collaboration skills with strong communication abilities and meticulous attention to detail
• Demonstrated scientific curiosity with a proactive approach to knowledge development and a track record of translating research findings into tangible products

Join our team and help shape the future of biotherapeutic production technologies at Revvity.