Senior Scientist, Bioprocessing R&D - CHO Expression

GBHB Revvity Discovery Limited

Cambridge

On-site

GBP 80,000 - 110,000

Full time

4 days ago
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Job summary

Revvity is seeking a Senior Scientist to join the Bioprocessing R&D team in Cambridge, UK. The role focuses on advancing CHO-based expression technologies for biotherapeutic production, tackling real‑world expression challenges and translating insights into commercial products for biopharma customers.

You will lead independent projects, evaluate new technologies, and collaborate across functions to drive platform differentiation while maintaining rigorous documentation and contributing to IP and

Qualifications

  • Ph.D. in life sciences with 5+ years postdoc or industry experience.
  • Deep CHO cell line development knowledge including stable pools, single-cell cloning, and screening.
  • Hands-on gene editing in mammalian cells, including targeted integration, knockout, and knock-in.
  • Experience expressing diverse biologics, including difficult-to-express proteins.
  • Strong molecular biology skills: Gibson, Golden Gate, PCR, qPCR, ddPCR.
  • Experience DoE in experimental design.
  • Ability to troubleshoot complex technical problems and work cross-functionally.
  • Excellent collaboration, communication, and documentation.

Responsibilities

  • Lead independent research projects to develop CHOSOURCE platform features for stable and transient expression applications.
  • Identify and evaluate emerging technologies and scientific trends to enhance platform performance.
  • Apply gene editing to engineer host cell lines with enhanced production characteristics.
  • Collaborate with peer senior scientists to drive cross‑functional problem-solving and advance platform capabilities.
  • Maintain comprehensive laboratory documentation and develop standard operating procedures.
  • Present clear, concise data at internal and external meetings.
  • Support IP generation and regulatory documentation as needed for product commercialization.
  • Foster collaborative relationships within the team and across Revvity departments.

Skills

CHO cell line development
Gene editing
Mammalian cell line engineering
Cloning (Gibson, Golden Gate)
PCR/qPCR/ddPCR
DoE (Design of Experiments)
Data analysis
Team collaboration
Scientific communication

Education

Ph.D. in life sciences (molecular biology, biochemistry, cell biology or genetics)

Job description

Revvity is seeking a Senior Scientist to join the Bioprocessing R&D team in Cambridge, UK. The role focuses on advancing CHO-based expression technologies for biotherapeutic production, tackling real‑world expression challenges and translating insights into commercial products for biopharma customers.

You will lead independent projects, evaluate new technologies, and collaborate across functions to drive platform differentiation while maintaining rigorous documentation and contributing to IP and

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