Senior Scientist - Gene Editing (Bioprocessing R&D)

1000scholars; Cambridge; Remote; GBP 65,000 - 90,000; Full time

Job summary

Revvity in Cambridge is seeking a Senior Scientist to lead gene editing projects in mammalian bioproduction cell lines, delivering high-quality results for client projects. You will design KO and KI strategies, work hands-on in the lab, and contribute to cell line development when needed.

The role requires strong molecular biology skills, experience with cloning techniques, and the ability to manage timelines with independence.

Qualifications

• MSc with PhD or equivalent in Life Sciences, Biochemical Engineering, or related field.
• Hands-on gene editing in mammalian cell lines with KO/KI strategies.
• Strong molecular biology skills including cloning techniques (Gibson/GGA), PCR, qPCR, and ddPCR.
• Ability to work independently and manage priorities to meet timelines.
• Strong data analysis and problem-solving abilities.
• Excellent written and verbal communication, with ability to present data clearly.
• Collaborative team player with proactive, solution-focused mindset.

Responsibilities

• Design and execute gene editing strategies (KO/KI) in mammalian bioproduction cell lines.
• Independently manage project workstreams and communicate progress to internal teams.
• Analyze experimental data and propose next steps.
• Maintain accurate lab records and SOPs.
• Present findings in internal meetings and reports.
• Collaborate with Bioprocessing team to ensure timely project delivery.
• Contribute to cell line development for expressing mammalian lines when needed.

Skills

Gene editing

Mammalian cell culture

Data analysis

Independent work

Communication

Team collaboration

Education

MSc with PhD or equivalent

Tools

Gibson Assembly

Golden Gate Assembly

PCR

qPCR

ddPCR

Job description

Senior Scientist - Gene Editing (Bioprocessing R&D)
Revvity
Cambridge, United Kingdom

Job Summary

As a Senior Scientist in the Bioprocessing R&D team, you will be primarily responsible for executing gene editing projects in mammalian bioproduction cell lines on behalf of clients, applying your expertise to design and implement targeted knockout (KO) and knock-in (KI) strategies. Working to defined project timelines and client requirements, you will bring strong technical independence and a delivery-focused mindset to ensure high-quality outcomes.
In addition to gene editing, you may also contribute to cell line development projects supporting the generation of expressing mammalian cell lines, broadening the scope of your impact within the team.
This is a hands-on, lab-based role suited to a scientist who thrives in a client-project environment, is comfortable working independently to deadlines, and brings a rigorous and methodical approach to experimental design and execution.

Key Responsibilities

• Design and execute gene editing strategies for KO and KI applications in mammalian bioproduction cell lines, planning and troubleshooting experiments to deliver high-quality, reproducible outcomes within agreed project timelines;
• Independently manage assigned project workstreams, ensuring timely delivery and maintaining clear communication with internal project teams;
• Analyse and interpret experimental data, drawing well-reasoned conclusions and proposing appropriate next steps;
• Maintain accurate and up-to-date laboratory records, including laboratory notebooks and relevant technical documentation such as SOPs and experimental reports;
• Communicate scientific results clearly and concisely in internal project meetings and written reports;
• Collaborate effectively with colleagues across the Bioprocessing team and wider organisation to support project delivery;
• Where required, contribute to cell line development activities supporting the generation of expressing mammalian cell lines for client projects.

Essential Competencies & Requirements

• MSc with PhD or equivalent experience in a relevant scientific discipline (Life Sciences, Biochemical Engineering, or closely related field);
• Demonstrated, hands-on expertise in gene editing with a strong track record of designing and executing KO and KI strategies in mammalian cell lines;
• Solid molecular biology skills, including proficiency in cloning techniques (e.g., Gibson Assembly, Golden Gate Assembly), PCR, qPCR, and ddPCR;
• Proven ability to work independently, manage priorities effectively, and deliver results within defined project timelines;
• Strong experimental design and data analysis skills;
• Highly organised, detail-oriented, and committed to producing reliable, reproducible scientific results;
• Excellent written and verbal communication skills, with the ability to present data clearly to internal stakeholders;
• Collaborative team player with a proactive and solution-focused approach.

Desirable Competencies & Requirements

• Experience in CHO cell line development and/or generation of expressing recombinant cell lines (stable pools and/or clones);
• Prior experience working in a client-facing or service-oriented research environment;
• Experience working in GLP or cGMP environments or a strong quality mindset aligned to regulated processes.