Senior Membrane Protein Biochemist – Expression & Purification

Evotec; Alderley; On-site; GBP 60,000 - 90,000; Full time

Benefits offered by this job

Pension scheme

25 days holiday + Bank holidays

Private health insurance

Wellbeing support

Private dental cover

Bonus scheme (discretionary)

Career progression & CPD

Cycle-to-work

Refer a friend scheme

Job summary

Evotec is seeking a Senior Scientist I (Membrane Protein Biochemist) to join the Alderley Park team. You will design and execute plans for production and characterization of membrane proteins, leading multiple projects and guiding internal resources to meet milestones.

You will work on advanced biophysical characterization and collaborate across discovery programs, contributing to scientific publications and Evotec’s reputation. A PhD and hands-on expression/purification expertise are essential.

Qualifications

• PhD in Biochemistry, Biophysics, Structural Biology or similar with industry experience in membrane protein expression and purification.
• Experience designing membrane protein constructs for functional expression in eukaryotic systems.
• Hands-on experience with insect and mammalian expression systems and multi-step chromatography purification (FPLC/HPLC).
• Expertise in optimizing expression/purification workflows to yield pure, stable membrane proteins.
• Experience with membrane protein targets (GPCRs, ion channels, SLCs) and related modalities.

Responsibilities

• Design and execute work plans for production and characterization of membrane proteins.
• Lead multiple projects and allocate internal resources to meet goals.
• Ensure data quality and alignment with project specifications.

Skills

Membrane protein biochemistry

Biophysics

GPCRs knowledge

Insect and mammalian expression

Protein purification workflows

Education

PhD in Biochemistry/Biophysics/Structural Biology

Tools

FPLC/HPLC

UHPLC

Mass spectrometry

Job description

Evotec is seeking a Senior Scientist I (Membrane Protein Biochemist) to join the Alderley Park team. You will design and execute plans for production and characterization of membrane proteins, leading multiple projects and guiding internal resources to meet milestones.

You will work on advanced biophysical characterization and collaborate across discovery programs, contributing to scientific publications and Evotec’s reputation. A PhD and hands-on expression/purification expertise are essential.