Senior LC-MS Method Development Lead

Nexus Life Sciences

Hemel Hempstead

On-site

GBP 50,000 - 60,000

Full time

5 days ago
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Benefits offered by this job

Leadership opportunity
Professional development
Training opportunities
Collaborative culture

Job summary

Nexus Life Sciences in Hemel Hempstead is seeking an experienced MS Method Development Lead to drive the development and validation of LCMSMS bioanalytical methods under GxP standards. This role combines technical expertise and team leadership.

The successful candidate will lead method development and validation, optimise extraction and chromatography, mentor the M&D team, ensure GLP compliance, support regulatory submissions, and drive continuous improvement in a cutting-edge bioanalytical lab

Qualifications

  • Degree in Biochemistry, Biomedical Science, or related field.
  • 4+ years in a GxP laboratory with at least 2 years in management.
  • Expertise in HPLC/UPLC/LCMSMS and chromatography data systems.

Responsibilities

  • Lead method development and validation as SME.
  • Optimize extraction techniques, chromatography methods, and LC columns.
  • Mentor the Method Development & Validation team.
  • Ensure GLP, SOPs, and regulatory guidelines compliance.
  • Troubleshoot methods and drive improvements.
  • Support regulatory submissions and CAPA initiatives.
  • Lead team meetings and staff development sessions.

Skills

HPLC
UPLC
LCMSMS
Method development
Leadership
Regulatory knowledge
SPE/PP extraction
DOE (preferred)
Mass Spectrometry data handling
Minitab/ Empower/ Mass Lynx

Education

Biochemistry / Biomedical Science degree

Tools

Empower
MassLynx
Minitab

Job description

Nexus Life Sciences in Hemel Hempstead is seeking an experienced MS Method Development Lead to drive the development and validation of LCMSMS bioanalytical methods under GxP standards. This role combines technical expertise and team leadership.

The successful candidate will lead method development and validation, optimise extraction and chromatography, mentor the M&D team, ensure GLP compliance, support regulatory submissions, and drive continuous improvement in a cutting-edge bioanalytical lab

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