Senior Bioinformatician: Multi-Omic & Single-Cell Genomics

Crick; Greater London; Hybrid; GBP 45,000 - 55,000; Full time

Benefits offered by this job

Leave allowance

Pension scheme

Health & wellbeing benefits

On-site restaurant

Job summary

The Francis Crick Institute is seeking a Bioinformatician to join the Malanchi Lab for a five-year ERC Synergy-funded programme. You will analyse genomic, transcriptomic and epigenetic datasets, including bulk and single-cell RNA-seq, ATAC-seq, ChIP-seq, methylome and proteomics data, and influence experimental design.

Collaboration with academic groups, development of tools, and translation of computational insights into biological hypotheses; strong programming, UNIX/Linux, and statistical

Qualifications

• A degree in Bioinformatics, Computer Science or a related discipline.
• Strong programming skills demonstrated in Python, R, Java, C/C++ or Perl.
• Experience applying statistical methods to biological data.
• Hands-on experience analysing next-generation sequencing, single-cell RNA-seq and ATAC-seq data.

Responsibilities

• Analysing and integrating large-scale genomic and multi-omic datasets.
• Working with bulk and single-cell RNA-seq, ATAC-seq, ChIP-seq, methylome and proteomic data.
• Developing computational approaches and algorithms to answer complex biological questions.
• Identifying patterns and signatures within datasets and translating these into meaningful biological insights.
• Working with scientists to inform experimental design and data interpretation.
• Developing and maintaining bioinformatics tools, software and databases.
• Ensuring data quality and integrity throughout the analysis process.
• Communicating findings through project discussions, presentations, reports and publications.
• Keeping up to date with emerging approaches and technologies across bioinformatics.

Skills

Bioinformatics degree

Programming

Statistics

NGS analysis

Single-cell RNA-seq

UNIX/Linux

Databases

Literature interpretation

Communication

Collaboration

Education

Degree in Bioinformatics/CS

Tools

Python

R

Java

C/C++

Perl

Job description

The Francis Crick Institute is seeking a Bioinformatician to join the Malanchi Lab for a five-year ERC Synergy-funded programme. You will analyse genomic, transcriptomic and epigenetic datasets, including bulk and single-cell RNA-seq, ATAC-seq, ChIP-seq, methylome and proteomics data, and influence experimental design.

Collaboration with academic groups, development of tools, and translation of computational insights into biological hypotheses; strong programming, UNIX/Linux, and statistical