Remote Senior Scientist, Structure-Based Modeling & MD/FEP

Deep Origin; United Kingdom; Remote; GBP 60,000 - 85,000; Full time

Benefits offered by this job

Competitive salary and equity packages

Flexible working hours

Remote-first team culture

Job summary

A forward-thinking biotechnology firm in the United Kingdom is looking for a Scientist/Senior Scientist to lead structure-based modeling initiatives. Your expertise in drug design and molecular dynamics will play a key role in transforming therapeutic discovery. The position offers competitive compensation, flexible hours, and a chance to work with an international team in a mission-driven environment.

Qualifications

• 2+ years of postdoctoral or industry experience.
• Hands-on expertise with FEP including setup, sampling, and analysis.
• Ability to work on US time zones when needed.

Responsibilities

• Analyze protein targets relevant to ADMET and off-targets.
• Run and refine docking, MD, and FEP simulations.
• Collaborate with teams to integrate insights across discovery pipelines.

Skills

Structure-based drug design

Molecular dynamics (MD)

Free energy perturbation (FEP)

Protein-ligand binding

Programming in Python

Fluent English

Education

Ph.D. in computational chemistry, structural biology, or biophysics

Tools

Schrödinger FEP+

OpenMM

GROMACS

AMBER

NAMD

MDAnalysis

PyMOL APIs

MDTraj

Job description

A forward-thinking biotechnology firm in the United Kingdom is looking for a Scientist/Senior Scientist to lead structure-based modeling initiatives. Your expertise in drug design and molecular dynamics will play a key role in transforming therapeutic discovery. The position offers competitive compensation, flexible hours, and a chance to work with an international team in a mission-driven environment.