Principal Scientist, Computational Chemistry (Remote UK)

Pharmaron; Hoddesdon; Remoto; GBP 70.000 - 110.000; Tempo pieno

Vantaggi offerti da questo lavoro

Flexible UK remote working environment

Global CRO/CDMO network

Access to AI-enabled technologies

Collaborative cross-disciplinary teams

Descrizione del lavoro

Pharmaron in the United Kingdom seeks an Associate Principal Scientist / Principal Scientist in Computational Chemistry to lead computational activities across drug discovery projects, from hit finding to lead optimisation, collaborating with medicinal chemistry, biology and DMPK teams.

You will apply cheminformatics, molecular modelling, AI-enabled design and develop new workflows within a flexible UK remote environment, mentoring others and contributing to client interactions and knowledge

Competenze

• PhD required in a relevant computational chemistry field.
• Significant experience in computational drug discovery.
• Experience with structure-based design and data-driven approaches.
• Exposure to AI/ML in drug discovery desirable.
• Excellent communication and presentation skills.

Mansioni

• Lead computational chemistry activities across integrated drug discovery projects from hit finding through lead optimisation and candidate selection.
• Design, evaluate and prioritise compounds using molecular modelling, structure-based drug design, virtual screening and cheminformatics approaches.
• Apply modern computational methodologies including AI/ML, molecular modelling and data-driven design strategies to support project progression.
• Collaborate closely with medicinal chemistry, biology and DMPK colleagues to guide compound design and decision making.
• Act as a key scientific contributor within multidisciplinary project teams.
• Present scientific recommendations and project updates to colleagues, collaborators and client partners.
• Contribute to the development and implementation of new computational workflows, tools and scientific capabilities.
• Mentor junior team members and contribute to knowledge sharing across the computational sciences group.
• Support scientific proposals, publications, conference presentations and business development activities.

Conoscenze

Computational Chemistry

Molecular Modelling

Cheminformatics

AI/ML in Drug Discovery

Cross-functional Collaboration

Mentoring/Leading

Formazione

PhD in Computational Chemistry / Molecular Modelling / Theoretical Chemistry

Descrizione del lavoro

Pharmaron in the United Kingdom seeks an Associate Principal Scientist / Principal Scientist in Computational Chemistry to lead computational activities across drug discovery projects, from hit finding to lead optimisation, collaborating with medicinal chemistry, biology and DMPK teams.

You will apply cheminformatics, molecular modelling, AI-enabled design and develop new workflows within a flexible UK remote environment, mentoring others and contributing to client interactions and knowledge