Molecular Modeller | Hybrid Work & AI-Driven Drug Design

Astex Pharmaceuticals; Cambridge; On-site; GBP 40,000 - 80,000; Full time

Benefits offered by this job

Hybrid working options

Training and career development opportunities

Onsite sports facilities

Competitive salary and benefits package

Job summary

An innovative firm is seeking a dynamic Molecular Modeller to join its Computer-Aided Drug Design group in Cambridge. This role offers the chance to apply cutting-edge structure-based design methods and cheminformatics tools in a collaborative environment. You'll work closely with biologists and chemists, utilizing over 19,000 proprietary protein-ligand structures to drive drug discovery efforts. With a focus on neurological disorders and oncology, this position provides an exciting opportunity to contribute to impactful projects while enjoying a flexible and inclusive work culture.

Qualifications

• Proven record of performing high caliber science in molecular modelling.
• Strong understanding of drug discovery and structure-based drug design.

Responsibilities

• Drive structure-based drug design from hit identification to lead optimization.
• Analyze protein-ligand structures and guide medicinal chemistry.

Skills

Computational Chemistry

Medicinal Chemistry

Structural Biology

Molecular Modelling

Programming (Python, R, Bash)

AI and Machine Learning

Drug Discovery

Communication Skills

Education

PhD in Computational Chemistry

Equivalent experience

Tools

Schrödinger

MOE

OpenEye

Cresset

Job description

An innovative firm is seeking a dynamic Molecular Modeller to join its Computer-Aided Drug Design group in Cambridge. This role offers the chance to apply cutting-edge structure-based design methods and cheminformatics tools in a collaborative environment. You'll work closely with biologists and chemists, utilizing over 19,000 proprietary protein-ligand structures to drive drug discovery efforts. With a focus on neurological disorders and oncology, this position provides an exciting opportunity to contribute to impactful projects while enjoying a flexible and inclusive work culture.