Protein Mass Spectrometry Research Scientist

LGC; England; On-site; GBP 55,000 - 75,000; Full time

Benefits offered by this job

25 days annual leave

Generous pension plan

Season ticket loans

Life assurance

Retail discounts

Job summary

The Protein Mass Spectrometry team at LGC delivers high quality measurement research to support government and private sector R&D in protein analysis. The role focuses on developing and validating MS-based methods, with emphasis on protein structure characterization and quantification, using advanced instruments and sample prep techniques.

The successful candidate will contribute to NML projects, publish findings, and collaborate with external partners while advancing their career in protein

Qualifications

• PhD (or equivalent) in industry, academic, or clinical research.
• Expertise in protein structure characterization methods involving MS (HDX-MS, native MS, IMS, XL-MS).
• Develop and optimise protein characterization methods, including intact mass analysis and peptide mapping.
• Experience with quantification approaches for peptides and proteins.
• Solid knowledge of protein chemistry workflows and sample preparation.
• Experience in protein separation and purification (HPLC, SPE, dialysis).
• Proficiency with MS instrumentation, operation and maintenance (Orbitrap, qTOF).
• Familiarity with bioinformatics tools for protein identification and characterization.
• Strong data analysis and interpretation skills for MS data.
• Excellent written and verbal communication and presentations.
• Experience managing long- and short-term research projects with deadlines.

Responsibilities

• Independently plan and deliver challenging R&D work with quality and budget focus.
• Lead protein and peptide metrology projects emphasizing structural analysis via MS.
• Publish and disseminate scientific advancements and results.
• Support formulation of R&D contracts for private sector work.
• Build relationships with external partners and extend metrology networks.
• Deliver ad-hoc research projects and provide comprehensive reporting.

Skills

Protein MS

HDX-MS

Native MS

IMS

XL-MS

Protein structure

Data analysis

Peptide quantification

Peptide mapping

HPLC

SPE

Dialysis

Bioinformatics

Communication

Project management

Education

PhD or equivalent

Tools

Orbitrap

qTOF

Ion mobility

HPLC

SPE

Dialysis devices

Job description

The Protein Mass Spectrometry team at LGC delivers high quality measurement research to support government and private sector R&D in protein analysis. The role focuses on developing and validating MS-based methods, with emphasis on protein structure characterization and quantification, using advanced instruments and sample prep techniques.

The successful candidate will contribute to NML projects, publish findings, and collaborate with external partners while advancing their career in protein