Postdoctoral Neuroscientist (iPSC & Neurodegeneration)

University-of-Oxford; Oxford; On-site; GBP 40,000 - 49,000; Full time

Job summary

University of Oxford in Oxford is seeking a scientifically skilled researcher to develop human cellular models of peripheral neuropathy using iPSC-derived sensory neurons. The role involves advanced culture techniques, microfluidic systems, and exposure to cellular stressors to explore disease mechanisms.

The post is full-time on a fixed term basis until 30 September 2028; the starting salary reflects Research Grade 7/6 with progression, and visa sponsorship support is available through HR.

Qualifications

• Interest in neural injury response and Wallerian degeneration pathways.
• Experience with molecular biology techniques and cellular models.

Responsibilities

• Develop human cellular models of peripheral neuropathy using iPSC-derived sensory neurons.
• Use microfluidic chambers and cellular stressors to model neuropathies.
• Investigate molecular pathways of cell death and axonal destruction via targeted approaches and genome-wide CRISPR screens.

Skills

Molecular biology

iPSC models

CRISPR screens

Tools

Microfluidic chambers

iPSC culture and differentiation

Job description

University of Oxford in Oxford is seeking a scientifically skilled researcher to develop human cellular models of peripheral neuropathy using iPSC-derived sensory neurons. The role involves advanced culture techniques, microfluidic systems, and exposure to cellular stressors to explore disease mechanisms.

The post is full-time on a fixed term basis until 30 September 2028; the starting salary reflects Research Grade 7/6 with progression, and visa sponsorship support is available through HR.