Postdoctoral Neuroscientist: iPSC Neuropathy & CRISPR

University of Oxford; Oxford; On-site; GBP 39,000 - 48,000; Full time

Job summary

The University of Oxford's Nuffield Department of Clinical Neurosciences invites applications for a Postdoctoral Neuroscientist at John Radcliffe Hospital in Oxford. The role focuses on developing human cellular models of peripheral neuropathy using iPSC-derived sensory neurons and advanced culture techniques.

You will investigate neural injury responses, Wallerian degeneration pathways and genome-wide CRISPR screens to map molecular regulators of cell death and axonal destruction.

Qualifications

• Interest in neural injury and iPSC models
• Experience with cellular biology techniques
• Familiarity with CRISPR screens and data analysis

Responsibilities

• Develop human cellular models of peripheral neuropathy using iPSC-derived sensory neurons
• Apply advanced culture techniques and cellular stressors to model neuropathies
• Investigate downstream molecular pathways mediating cell death and axonal destruction with targeted and genome-wide approaches

Job description

The University of Oxford's Nuffield Department of Clinical Neurosciences invites applications for a Postdoctoral Neuroscientist at John Radcliffe Hospital in Oxford. The role focuses on developing human cellular models of peripheral neuropathy using iPSC-derived sensory neurons and advanced culture techniques.

You will investigate neural injury responses, Wallerian degeneration pathways and genome-wide CRISPR screens to map molecular regulators of cell death and axonal destruction.