Computational Protein Design Research Assistant

University of Bristol; West of England; Presencial; GBP 26.000 - 38.000; Jornada completa

Descripción de la vacante

The University of Bristol invites applications for a Research Support Assistant to join the multi-institutional PIONEER programme in the School of Biochemistry and Biomedical Sciences. You will work with Prof. Ross Anderson, Prof.

Mark Szczelkun and a collaboration of researchers, focusing on computational biology and protein engineering. This role is ideal for a recent graduate or early-career researcher seeking training in AI-based design tools, structure prediction, and high-performance

Formación

• Degree in a relevant scientific discipline with enthusiasm for a research career in computational biology or protein engineering.
• Experience with computational protein design methods and data analysis.
• Experience with protein structure prediction tools such as AF3 and Boltz-2.

Responsabilidades

• Design protein and peptide binders using computational methods and AI-based design tools.
• Use structure prediction platforms on HPC clusters to develop design pipelines.
• Perform molecular dynamics simulations to evaluate protein structures.
• Collaborate with researchers and software engineers to support project development on Isambard-AI.
• Collaborate with laboratory researchers to experimentally characterise designed proteins and peptides.
• Analyse and present findings at meetings and contribute to publications.
• Maintain accurate research records and contribute to reporting and milestones.
• Support and train students or colleagues in computational methodologies.

Conocimientos

Computational protein design

Data analysis

High-performance computing

Educación

Bachelor's degree in a relevant scientific discipline

Herramientas

AF3

Boltz-2

ESMFold2

RFDiffusion3

proteinMPNN

DiffDock

Descripción del empleo

The University of Bristol invites applications for a Research Support Assistant to join the multi-institutional PIONEER programme in the School of Biochemistry and Biomedical Sciences. You will work with Prof. Ross Anderson, Prof.

Mark Szczelkun and a collaboration of researchers, focusing on computational biology and protein engineering. This role is ideal for a recent graduate or early-career researcher seeking training in AI-based design tools, structure prediction, and high-performance