Remote Computational Structural Biologist - AI-Driven

Bindbridge; Cambridge; Remote; GBP 65,000 - 110,000; Full time

Job summary

Bindbridge is seeking a Computational Structural Biologist to join an remote, UK-focused team building AI-driven molecular glue discovery for sustainable agriculture. You will lead computational studies of protein structures, develop scalable data pipelines and reusable software, and collaborate with experimentalists and engineers to translate findings into actionable insights.

Applicants should have a strong background in structural biology, experience with computational methods on proteins,

Qualifications

• Postgraduate degree or equivalent experience in computational structural biology.
• Experience using computational methods to study protein structures or complexes.
• Strong programming and software engineering for scientific software.
• Experience building data pipelines and working with databases.
• Ability to define research questions and draw defensible conclusions.
• Experience interpreting data from structural/biophysical methods.
• Excellent written and verbal communication; ability to lead research across disciplines.

Responsibilities

• Lead computational studies of protein structures, complexes and molecular glue-induced interactions using methods such as structure prediction, co-folding, docking, molecular dynamics and integrative modelling.
• Work with experimental scientists and advisers to incorporate structural and biophysical evidence into models, understand its limitations and identify useful follow-up experiments.
• Write, test and maintain reusable scientific software for structural modelling, analysis and evaluation, contributing directly to shared codebases and working with AI and software engineers to integrate, deploy and scale it.
• Design and build data pipelines that ingest, validate, harmonise and version structural, sequence, experimental and computational data.
• Develop and maintain data models and databases that connect proteins, structures, experiments, predictions and results, with clear quality controls, metadata and provenance.
• Design benchmarks and evaluations that show where computational approaches work, where they fail and how confidently their results can be used.
• Document methods, assumptions, limitations and results, then communicate their scientific implications across disciplines.

Skills

Computational structural biology

Protein structure understanding

Programming

Data pipelines

Documentation

Team collaboration

Education

Postgraduate degree in computational biology

Tools

Python

Linux

Git

Job description

Bindbridge is seeking a Computational Structural Biologist to join an remote, UK-focused team building AI-driven molecular glue discovery for sustainable agriculture. You will lead computational studies of protein structures, develop scalable data pipelines and reusable software, and collaborate with experimentalists and engineers to translate findings into actionable insights.

Applicants should have a strong background in structural biology, experience with computational methods on proteins,