POSTDOC_068_MM - H/F

Inserm France; Illkirch-Graffenstaden; Hybrid; EUR 42,000 - 56,000; Full time

Job summary

Inserm France is seeking a postdoctoral researcher to lead subcellular transcriptomics in embryonic stem cells for Aim 1. You will perform TimeLapse-seq and isolate RNA fractions to quantify RNA synthesis, processing, export and decay, in control and TIP60-depleted cells.

You will coordinate sequencing QC, integrate results with Bayesian kinetic modelling and smFISH partners, and contribute to data management, consortium meetings, reports and manuscripts.

Qualifications

• PhD required in life sciences, molecular biology, cell biology or related field.
• Experience with mouse embryonic stem cells is essential.
• Auxin-inducible coactivator depletion and RNA metabolic labelling familiarity preferred.
• Subcellular fractionation and transcriptomics/NGS experience required.

Responsibilities

• Lead subcellular TimeLapse-seq in mouse embryonic stem cells.
• Isolate chromatin-associated, nuclear, cytoplasmic and polysome-bound RNA; quantify RNA dynamics.
• Coordinate sequencing and QC; integrate results with modelling and partners.

Skills

RNA biology

Stem-cell culture

Subcellular fractionation

Transcriptomics/NGS

Quantitative data analysis

Experimental autonomy

Scientific writing

Teamwork

English proficiency

Education

PhD in life sciences

Job description

About the position

The postdoctoral researcher will lead subcellular transcriptomics in embryonic stem cells for Aim 1.

Main activities : Perform subcellular TimeLapse-seq in control and acutely TIP60-depleted mouse embryonic stem cells; isolate chromatin-associated, nuclear, cytoplasmic and polysome-bound RNA; quantify RNA synthesis, processing, export and decay.

Associate activities : Coordinate sequencing and quality control; integrate results with Bayesian kinetic modelling and smFISH partners; contribute to data management, consortium meetings, reports and manuscripts.

Desired profile

Specific Requirements or Constraints : Work with mouse embryonic stem cells, auxin-inducible coactivator depletion, RNA metabolic labelling and subcellular fractionation; follow IGBMC safety, ethics and data-management procedures.

Skills/Qualifications : Strong RNA and molecular biology skills; mammalian or stem-cell culture; subcellular fractionation; transcriptomics/NGS; quantitative data analysis; experimental autonomy; scientific writing and teamwork.

English : fluent scientific working proficiency.

Application requirements

Required document(s)

Position characteristics

Published on 09/25/2026

Contractuel Catégorie A Fixed-term contract - 12 months Full time Experience required License not required > Master degree level PhD in life sciences, molecular biology, cell biology or related field.