Engineering positions on spatial genomics

France - BioImaging; Montpellier; Sur place; EUR 35 000 - 50 000; Plein temps

Résumé du poste

France - BioImaging in Montpellier is seeking engineers to work on spatial genomics. Candidates will investigate chromatin organization during meiosis in mice and develop imaging-based omics strategies.

Expertise in microscopy and molecular biology is essential, with responsibilities including amplifying oligopaint libraries and analyzing spatial genomics datasets. The position aims to unravel the mechanisms of DNA organization and epigenetic marks in various samples.

Starting date is as early as January 1, 2026.

Qualifications

• Expertise in microscopy and/or molecular biology.
• Experience in amplifying oligopaint libraries and performing DNA-FISH.
• Familiarity with image analysis for spatial genomics datasets.

Responsabilités

• Investigation of chromatin organization during meiosis.
• Designing strategies to image epigenetic marks in cancer models.
• Preparing chromosome spreads/squash from spermatocytes.

Connaissances

Microscopy expertise

Molecular biology

DNA-FISH

Image analysis tools

Oligopaint libraries

Sequencing-based technologies

Description du poste

Engineering positions on spatial genomics

Available from:January 1, 2026

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CNRS Jobs

Position Information:

Marcelo Nollman’s team in CBS (Center for Structural Biochemistry, Montpellier), is looking for two engineers to work on spatial genomics. The team is interested in understanding the mechanisms of DNA organization and remodeling by building state-of-the-art microscopes, and image analysis tools.

Project 1

The project 1 is centered on the use spatial genomics to investigate the mechanisms driving chromatin organization during meiosis in mice.

Candidate 1 will have expertise in microscopy and/or molecular biology, and will be in charge of amplifying oligopaint libraries, performing DNA-FISH, preparing chromosome spreads/squash from spermatocytes, and acquiring and analyzing spatial genomics datasets.

Project 2

The project 2 consists in the development of imaging-based spatial multi-omics to visualize epigenetic marks and 3D chromatin organization in Drosophila, mouse and human samples.

Candidate 2 will have experience in molecular biology and sequencing-based technologies, and will be in charge of designing and validating spatial multi-omics strategies to image epigenetic marks in cancer models.

Find more details on the projects on the PDF attached.

General informations

Starting date: As early as 1 January 2026