Senior COA Scientist, Scoring & Interpretation

Jobtailor; Frankfurt; Vor Ort; EUR 90.000 - 120.000; Vollzeit

Zusammenfassung

Jobtailor is seeking a senior COA Scientist to lead evaluation and implementation of clinical outcome assessments, ensuring scientifically robust score structures and documentation for use in regulated clinical research.

You will collaborate with cross-functional teams to translate scientific requirements into validated scoring implementations, drive data handling rules, and provide interpretation guidance for COA scores in a fast-paced environment.

Qualifikationen

• Advanced degree in a relevant field and pharma/healthcare research experience.
• Experience with instrument development, validation and psychometric evidence.
• Strong interpretation skills of scoring methodologies for COA.

Aufgaben

• Provide scientific leadership across COA evaluation and implementation, ensuring outputs are robust for clinical research use.
• Contribute to COA science by reviewing deliverables and strengthening scalable processes.
• Interpret manuals and source materials to define valid scoring requirements, including structure and weighting.
• Define missing-data handling rules and algorithm requirements where guidance is unclear.
• Assess interpretation guidance for COA scores, including severity bands and benchmarks.
• Collaborate with statisticians, programmers, product, and engineering to translate requirements into validated scoring implementations.
• Investigate discrepancies and support robust resolution of scoring-related issues.
• Serve as scientific point of contact for scoring logic and feasibility in implementation.
• Contribute to SOPs and templates to improve scoring operations.

Kenntnisse

COA Science Expertise

Scoring Methodology Interpretation

Instrument Development Experience

Stakeholder Management Skills

Advanced Degree in Relevant Discipline

Ausbildung

PhD / MSc / MPH / PharmD / Psychometrics / Epidemiology

Jobbeschreibung

• Provide scientific leadership across COA evaluation and implementation, applying expertise in measure development, instrument documentation, scoring methodology, and interpretation to ensure outputs are scientifically robust and fit for clinical research use.


• Contribute to high-quality COA science across the organisation by supporting methodological best practices, reviewing scientific deliverables, collaborating with cross-functional teams, and strengthening scalable processes for both instrument-related and scoring-related work.


• Interpret scoring manuals, instrument documentation, publications, and related source materials to define scientifically valid, implementation‑ready scoring requirements, including score structures, derivations, recoding, transformations, weighting, and conditional logic.


• Define and document missing‑data handling rules, minimum completion thresholds, suppression logic, and other algorithm requirements where source guidance is incomplete, ambiguous, or complex.


• Assess and document interpretation guidance associated with COA scores, including severity bands, score meaning, benchmarks, and other clinically relevant interpretation outputs where supported.


• Identify, evaluate, and resolve ambiguities in scoring methodology, escalating appropriately when scientific judgement, author clarification, or senior SME input is required.


• Partner with statisticians, programmers, product, and engineering teams to translate scientific requirements into validated scoring implementations.


• Investigate discrepancies, implausible outputs, and scoring‑related issues to determine root cause and support robust resolution.


• Serve as the scientific point of contact for internal queries related to scoring logic, interpretation, algorithm complexity, and implementation feasibility.


• Contribute to standard templates, SOPs, review checklists, and reusable scientific assets that improve the quality, consistency, and scalability of scoring operations.

Requirements

• Advanced degree (PhD, MSc, MPH, PharmD, psychology, outcomes research, public health, psychometrics, epidemiology, health sciences, or related discipline).


• Minimum 7 years of relevant experience in COA science, outcomes research, psychometrics, patient‑centered research, or closely related scientific roles within pharma, CRO, healthcare research, or instrument development.


• Experience with instrument development, validation, psychometric evidence, or interpretation / meaningful‑change work.


• Deep familiarity with COA concepts, including domains, scoring structures, recall periods, missing‑data rules, interpretation, and fit‑for‑purpose use in clinical research.


• Strong, demonstrable experience interpreting and applying scoring methodologies for clinical outcome assessments, including at least some experience beyond simple sum or average scoring.


• Demonstrable experience translating scientific source materials into structured documentation, specifications, reports, or implementation guidance.


• Ability to evaluate ambiguous or incomplete source documentation and make sound, well‑documented scientific judgements or escalations.


• Strong stakeholder management skills and ability to work across scientific, operational, quantitative, and technical teams.


• Excellent written English and strong documentation discipline.


• Experience supporting regulated or audit‑sensitive clinical research workflows.


• Experience supervising or reviewing work from more junior scientists, analysts, or cross‑functional partners.


• No visa sponsorship available.


• CV must be submitted in English.

Core Competencies

Demonstrates expertise in COA evaluation and implementation, with a strong focus on scoring methodology, instrument documentation, and psychometric principles. Proven ability to translate scientific requirements into actionable documentation and collaborate effectively across multidisciplinary teams.

Highest‑signal resume keywords

• COA Science Expertise


• Scoring Methodology Interpretation


• Instrument Development Experience


• Stakeholder Management Skills


• Advanced Degree in Relevant Discipline

Hard Skills

• Measure Development


• Instrument Documentation


• Scoring Methodology


• Psychometric Evidence


• Data Handling Rules


• Statistical Analysis


• Documentation Specifications


• Clinical Outcome Assessments


• Missing‑Data Rules


• Interpretation Guidance

Soft Skills

• Strong Communication Skills


• Collaboration


• Problem‑Solving


• Attention to Detail


• Leadership

Industry Keywords

• Clinical Research


• Patient‑Centered Research


• Pharma


• CRO


• Healthcare Research


• Outcomes Research


• Psychometrics


• Epidemiology


• Health Sciences


• Regulated Workflows