Research Assistant (Postdoc)

Philipps-Universität; Marburg; Presencial; EUR 52.000 - 70.000; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

Gleiche Bezahlung gemäß Hessen-Tarif

Firmen-/Universitäts-Ticket für ÖPNV

Karriereentwicklung für Nachwuchsw科学en

Descripción de la vacante

Die Philipps-Universität Marburg sucht eine Postdoc-Position in der Forschungsgruppe Entwicklungsgenetik und Zellbiologie von Tieren. Die Tätigkeit umfasst Entwurf und Klonierung optischer Biosensoren zur GPCR-Konformationsanalyse sowie Validierung in lebenden Zellen.

Sie arbeiten an GPCR‑Antworten auf Liganden, führen mikroplattenbasierte Assays durch und modellieren GPCR–Ligand‑Interaktionen. Die Stelle ist befristet auf 3 Jahre mit TV-H E13, Vollzeit.

Formación

• Abgeschlossenes MSc-Studium in Lebenswissenschaften oder gleichwertig; Promotion oder kurz vor Abschluss
• Umfangreiche molekularbiologische Techniken zur Klonierung neuer Fusionsproteine
• Erfahrung mit pharmakologischen Tests in lebenden Zellen in Mikroplattenformat (≥96-well)
• Frühere Arbeiten zu GPCR, G-Protein, GRK oder Arrestin-bezogenen Forschungsfragen
• Gute Englischkenntnisse; wünschenswert: Erfahrung mit Biosensor-Design in lebenden Zellen

Responsabilidades

• Entwurf und Klonierung optischer Biosensoren zur Messung konformationsbedingter GPCR-Dynamik
• Validierung von Biosensoren in lebenden Zellen
• Anwendung von Biosensoren zur Charakterisierung GPCR-Rezeptor-Antworten auf Liganden und mechanische Signale
• Design und Durchführung pharmakologischer Zellbiologie-Assays in Mikroplatten (≥96-well)
• Analyse und Visualisierung großer pharmakologischer Datensätze
• Strukturelle Modellierung von GPCR–Ligand-Interaktionen

Conocimientos

GPCR-Forschung

Molekularbiologie

zelluläre Assays

Datenanalyse

Englische Sprachkenntnisse

Educación

MSc in Lebenswissenschaften

Ph.D. in Lebenswissenschaften oder kurz vor Abschluss

Herramientas

Optische Biosensoren

96-Well-Mikroplatten-Assays

Descripción del empleo

registration number:
fb17-0029-wmz-2026

Entry date:
as soon as possible

Application deadline:
2026-11-22

Salary:
E 13 TV-H

Duration:
3 years

Volume of employment:
fulltime

The University of Marburg, founded in 1527, offers a variety of excellent programs of study for around 22,000 students and confronts the important topics of our time through excellent research across a broad spectrum of sciences.

The Department of Biology research group on “Developmental Genetics and Cell Biology of Animals”, Prof. Dr. Christian Helker, is currently accepting applications for a

Research Assistant (Postdoc)

The position is offered for a period of 3 years, if no former times of qualification must be considered. The starting date is as soon as possible. The position is fulltime with salary and benefits commensurate with a public service position in the state Hesse, Germany (TV-H E 13).

Tasks:

• design and cloning of optical biosensors to measure conformational dynamics of G protein-coupled receptors (GPCRs)
• validation of optical biosensors in living cells
• application of optical biosensors to characterize GPCRs responses to ligand and mechanical signals
• design and performance of pharmacological, cell biological assays in microtiter plates (≥ 96-well)
• analysis and visualisation of large pharmacological datasets
• Structural modeling of GPCR–ligand interactions

The position will be filled by a temporary contract that is limited to the period which is necessary to gain further scientific expertise (such as the preparation for a subsequent qualification period). Within the entrusted tasks the opportunity for independent scientific work to obtain further personal qualification is given. The limitation complies with Section 2 (1) of the German Academic Fixed-Term Contract Act (WissZeitVG).

Profile:

• MSc degree or equivalent and a Ph.D. in the life sciences or evidence of near completion of doctoral studies
• extensive experience in molecular biology techniques required for the cloning of new fusion proteins
• extensive experience in performing pharmacological assays in living cells in microtiter plate format (≥ 96-well)
• previous work on GPCR, G protein, GRK or arrestin related research questions
• experience in the design and validation of new biosensors used in living cells is desireable
• very good English skills

We offer:

• equal Pay according to the Hesse Collective Agreement
• ticket for free use of public transport in the state Hesse, Germany
• career development training for junior scientists including postdoctoral researchers
• A collaborative, innovative, and supportive research environment
• Professional development opportunities, including training, coaching, and mentoring

Contact for more Information

Lilli Backhaus

[phone]

[e-mail]

We support women and strongly encourage them to apply. In areas where women are underrepresented, female applicants will be preferred in case of equal qualifications. As a certified family-friendly university, we support our employees in balancing family and career. A reduction of working time is possible. Applicants with a disability as discribed in theSocial Security Code (Section 2(2) and (3) of Book IX of the Social Security Code (SGB IX))will be preferred in case of equal qualifications. Application and interview costs can not be refunded.