Postdoctoral Researcher (m/f/d)

Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.; Dortmund; Vor Ort; EUR 45.000 - 60.000; Vollzeit

Zusammenfassung

Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. seeks a Postdoctoral Researcher in Dortmund. The role involves studying the phosphorylation sites impacting mitosis, utilizing biochemical reconstitutions and collaborating with an interdisciplinary team. Candidates should possess a PhD in a relevant field and a strong publication record. This fixed-term position offers a rich scientific environment and the chance to explore cutting-edge research in cell biology.

Qualifikationen

• PhD in relevant scientific area with at least one first author publication.
• Strong background in biochemistry and relevant techniques.
• Experience working on mitosis is an advantage.

Aufgaben

• Examine how mitosis is regulated by dynamic phosphorylation sites.
• Use biochemical reconstitutions to unravel de/phosphorylation rates.
• Work collaboratively in an interdisciplinary team.

Kenntnisse

Biochemical reconstitutions

Mass spectrometry

Collaborative work

Scientific writing

PhD in relevant scientific area

Ausbildung

PhD in a relevant scientific area

Tools

Mass spectrometry

Cell biology techniques

Jobbeschreibung

Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology (Dortmund, DE)
Full time
Financial compensation according to the public service remuneration scheme TVöD BUND

We are recruiting a Postdoctoral Researcher (m/f/d) to join the laboratory of Prof. Andrea Musacchio in the Department of Mechanistic Cell Biology at the Max Planck Institute of Molecular Physiology in Dortmund, Germany. This is a fixed-term appointment for 36 months in the first instance, with possible extension thereafter.

We are looking for a talented ambitious postdoctoral researcher to join an 8-year Wellcome Trust-funded team project. The goal is to study a fundamental property of all phosphorylation sites, for which almost nothing is currently known: the speed at which individual molecules are phosphorylated and dephosphorylated over time. The interdisciplinary team assembled to tackle this has expertise in kinase and phosphatase signalling (Adrian Saurin, University of Dundee), mass spectrometry (Tony Ly, University of Dundee) and biochemical reconstitutions (Andrea Musacchio in Dortmund). These approaches will be used to study how dynamic phosphorylation sites that continually “flash” on and off regulate key signalling properties during mitosis. A major goal is to understand how these sites are important to regulate kinetochores and chromosome segregation, and why this may fail to drive cancer progression. This position is primarily to use biochemical reconstitutions in vitro, but there is the possibility for the candidate to transit between labs and learn mass spectrometry and cell biology.

For further information about this position please contact Andrea Musacchio at Email .

Priorities will include:

• Examining how mitosis is regulated by dynamic phosphorylation sites
• Using complex biochemical reconstitutions of mitotic pathways, such as those that trigger the spindle checkpoint and microtubule attachment errors, to unravel global de/phosphorylation rates
• Working effectively and collaboratively as part of an interdisciplinary team

Who we are looking for:

• A highly-motivated and ambitious postdoctoral researcher with a passion for science
• Motivated, honest, hard-working, collaborative, organized
• A candidate with a PhD in relevant scientific area, with at least one first author publication
• A strong scientific background in biochemistry with experience of relevant techniques and/or working on the mitosis

Additional Information

The Max Planck Society is committed to increasing the number of individuals with disabilities in its workforce and therefore encourages applications from such qualified individuals.

The Max Planck Society seeks to increase the number of women in those areas where they are underrepresented and therefore explicitly encourages women to apply.

The Max Planck Society is committed to diversity and equal opportunity and strongly encourages applications from underrepresented groups.