PostDoc Position in Extracellular Vesicle Biology (m/f/d)

Roche; Penzberg; On-site; EUR 60,000 - 78,000; Full time

Job summary

Roche is seeking a highly motivated Postdoctoral Fellow (m/f/d) to join the Discovery Sciences team. The role focuses on enriching and analyzing extracellular vesicles to explore diagnostic potential, with responsibilities spanning design, execution and analysis of wet-lab experiments.

Embedded within the Discovery Sciences Chapter at Roche Diagnostics GmbH, the position is part of a high-impact group driving next-generation diagnostic solutions.

Qualifications

• PhD in Molecular Biology, Biochemistry, or related field with 3+ years of experimental research and publications.
• Deep expertise in extracellular vesicles biology and lab techniques such as immunoprecipitation, SEC, AF4, and immunoassays.
• Experience with RNA isolation and RNA sequencing.
• Fluency in English and strong communication skills.

Responsibilities

• Perform enrichment of EVs from human matrices via immunoprecipitation and other methods.
• Analyze enriched EVs using state-of-the-art methods including mass spectrometry and sequencing.
• Collaborate with bioinformatics, assay development, and sequencing teams to evaluate EVs for diagnostics.
• Drive interdisciplinary meetings to share data and contribute to Diagnostics strategy.
• Document findings for patent filings and present at conferences.

Skills

Peer-reviewed publications

Analytical mindset

Interdisciplinary collaboration

Scientific communication

Education

PhD in Molecular Biology/Biochemistry/Cell Biology

Tools

Immunoprecipitation

Size Exclusion Chromatography

Asymmetrical Flow Field-Flow Fractionation

ELISA

Western Blot

RNA isolation

RNA sequencing

Mass spectrometry

Job description

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

We are looking for a highly motivated and talented Postdoctoral Fellow (m/f/d) to join our Discovery Sciences team. In this role you will be at the forefront of Science, enriching and analyzing Extracellular Vesicles (EVs) in order to deduce a diagnostic potential and address different medical needs. Your responsibilities will encompass the design, execution, and analysis of wet-lab experiments.

This position is embedded within the Discovery Sciences Chapter at Roche Diagnostics GmbH. As part of the Technology Program, you will join a high-impact team of researchers dedicated to pioneering next-generation diagnostic solutions.

Our culture is defined by trust, transparency, and a strong collaborative spirit. We are looking for a proactive colleague who balances independent critical thinking with team spirit and the flexibility to collaborate across diverse departments and interdisciplinary teams.

Your tasks

• Perform the enrichment of EVs from human matrices, predominantly via immunoprecipitation, but also other methods like SEC, dUC and AF4
• Analysis and quality assessment of the enriched EVs with different state-of-the-art methods and technologies (targeted and untargeted like mass spectrometry, RNA sequencing, luminescence) in cooperation with other departments
• Partner with bioinformatics, assay development, and sequencing teams to evaluate the applicability of the captured EVs for diagnostic platforms.
• Drive interdisciplinary meetings to share data, leverage expertise across functions, and contribute to the broader Diagnostics strategy
• Document findings for patent filings and present research in stakeholder meetings, scientific journals, and international conferences

This position requires handling of human fluid samples, i.e. potentially infectious material (Biosafety Level 2, "Infektionsschutzgesetz") under company safety standards.

Your profile

• You have successfully completed a PhD in Molecular Biology, Biochemistry, Cell Biology or a related field including 3+ years of experimental research experience and a strong track record of peer-reviewed publications
• You have deep expertise in the biology, enrichment and analysis of Extracellular Vesicles as well as the respective laboratory techniques, such as immunoprecipitation, size exclusion chromatography, asymmetrical flow field-flow fractionation, and immunoassays like ELISA and Western Blot,
• Your profile is complemented by proficiency in working with nucleic acids like RNA isolation and RNA sequencing
• Your knowledge and application of statistical concepts is considered a plus
• You are goal-oriented and eager to establish new wet-lab techniques and scientific concepts
• Your personal drive and your ability to learn and take over responsibility is a key value for us
• You possess excellent communication skills and fluency in English

When does it start?

This position should be filled with effect January 2027 and is limited to 2 years.

Your contact to us! With people. For people.

Do you need further support?

Please have a look at our FAQs, you will find them via https://careers.roche.com/global/en/faq.

Who we are

A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let's build a healthier future, together.

Roche is an Equal Opportunity Employer.