PhD student (f/m/d) | Cellular Resilience

Max Planck Group; Bad Nauheim; Sur place; EUR 17 000 - 23 000; Plein temps

Résumé du poste

The Max Planck Institute for Heart and Lung Research in Bad Nauheim invites applications for a PhD student (f/m/d) in the Research Group Cellular Resilience. The position is available for three years starting on 1 January 2027, with a later starting date possible.

The successful candidate will join an international team working at the interface of cell biology and RNA biology. You will investigate how RNA-binding proteins shape cellular stress responses, establish sequencing and proteomics

Qualifications

• Master's degree in biology, biochemistry, or related field.
• Experience in cell culture and molecular biology, incl. cloning and CRISPR-Cas.
• Experience in RNA biology and/or high-throughput sequencing.
• Proficiency in R or Python for data analysis.
• Excellent English communication.
• Strong teamwork and creative thinking.

Responsabilités

• Conduct independent research project investigating the role of RNA-protein interactions in cellular stress responses.
• Establish and develop next-generation sequencing and mass spectrometry-based proteomic approaches and analyse the resulting data.
• Contribute to the preparation of scientific publications.
• Present research findings at internal seminars and international conferences.
• Stay up to date with relevant scientific literature.

Connaissances

Cell culture

Molecular biology

Cloning

CRISPR-Cas

RNA biology

Data analysis (R/Python)

English communication

Teamwork

Formation

Master’s degree in biology/biochemistry or related field

Description du poste

The Max Planck Institute for Heart and Lung Research, W. G. Kerckhoff Institute, Bad Nauheim, Research Group Cellular Resilience (Group leader: Dr. Reymond Sutandy), invites applications for a PhD student (f/m/d), ref. nr. 2026_24.

The position is available for three years, starting on 1 January 2027. A later starting date can be arranged.

The Max Planck Institute for Heart and Lung Research in Bad Nauheim is an internationally renowned research institute. It conducts basic research primarily in the field of the cardiovascular system and organ biology. The institute currently comprises three departments, several independent research groups, and central scientific service groups. A total of approximately 380 people are currently employed at the institute.

Job description

Cells are constantly exposed to intrinsic and environmental stressors that challenge cellular homeostasis. To ensure survival, cells have evolved intricate stress response pathways that detect diverse insults and coordinate adaptive programmes. Understanding how these responses are integrated is a central challenge in cell biology, as their dysregulation contributes to numerous human diseases. Our group investigates how cells sense stress, mount adaptive responses, and restore homeostasis to maintain cellular resilience. We combine human cellular models with transcriptomic and proteomic approaches to uncover the molecular mechanisms that coordinate interconnected cellular stress response pathways. We are seeking a highly motivated and curious individual who is eager to contribute to cutting-edge research and grow with our team. The successful candidate will investigate how RNA-binding proteins shape cellular stress responses and adaptation.

Your responsibilities

• Conduct an independent research project investigating the role of RNA-protein interactions in cellular stress responses
• Establish and develop next-generation sequencing and mass spectrometry-based proteomic approaches and analyse the resulting data
• Contribute to the preparation of scientific publications
• Present research findings at internal seminars and international conferences
• Stay up to date with relevant scientific literature

Your qualifications

• A completed scientific university degree (Master’s degree or equivalent; candidates close to completion are also encouraged to apply) in biology, biochemistry, or a related discipline, with a strong focus on molecular biology, cell biology, or biochemistry
• Hands-on experience in cell culture and molecular biology techniques, including cloning and CRISPR-Cas technologies, is highly desirable
• Previous research experience in RNA biology and/or high-throughput sequencing technologies would be a strong advantage
• Familiarity with programming languages such as R or Python for data analysis is beneficial
• Excellent communication skills in English
• Ability to work effectively in a team and think creatively is highly valued

Our offer

• An opportunity to work in an international team
• Our researchers have the opportunity to work on various model systems by making use of the latest cutting-edge technologies
• Researchers are supported by state-of-the-art core facilities which offer services in next-generation sequencing, proteomics, bioinformatics, cytometry, microscopy, and small animal imaging

The Max Planck Society is committed to increasing the number of individuals with disabilities in its workforce and therefore encourages applications from such qualified individuals. Furthermore, the Max Planck Society strives for gender and diversity equality. We welcome applications from all backgrounds.