10x Genomics Single-Cell Lab Technician

BMKGENE Europe; Münster; On-site; EUR 42,000 - 62,000; Full time

Job summary

BMKGENE Europe is seeking a hands-on Biology Research Associate in Münster to lead end-to-end single-cell sequencing workflows. You will preprocess samples, perform cell dissociation, run library preparation, and ensure data quality.

You will use platforms such as 10x Genomics, conduct PCR/qPCR, and work with human and mouse tissues. Strong English communication and collaboration with cross-functional teams are essential.

Qualifications

• Master’s degree with 1–3 years hands-on laboratory experience.
• Hands-on experience with single-cell sequencing platforms (10x Genomics or equivalent).
• Experience with tissue dissociation and single-cell preparation.
• Proficiency in PCR, qPCR and NGS workflows.
• Good communication in English; willing to travel.

Responsibilities

• Perform end-to-end single-cell sequencing workflows from sample prep to library prep.
• Execute and optimize single-cell experiments using platforms like 10x Genomics.
• Conduct molecular biology experiments including PCR, qPCR and NGS-related workflows.
• Handle human and mouse tissue samples and optimize protocols to improve data quality.
• Operate laboratory instruments such as flow cytometers and PCR/qPCR systems.
• Analyze results, maintain records, and report findings to internal teams.
• Troubleshoot experiments and contribute to protocol development.
• Collaborate with researchers and assist in mentoring junior staff.

Skills

Single-cell sequencing

Flow cytometry / FACS

Molecular biology techniques

Education

Master’s degree in Biology or related field

Tools

10x Genomics platform

NGS workflows

Job description

• Perform end-to-end single-cell sequencing workflows, including sample processing, single-cell dissociation, single-nucleus preparation, cell sorting, quality assessment, and library preparation.
• Execute and optimize single-cell experiments using platforms such as 10x Genomics, PARSE, or other single-cell technologies.
• Conduct molecular biology experiments including PCR, qPCR, nucleic acid extraction/purification, and NGS-related workflows.
• Handle human and mouse tissue samples and optimize protocols for challenging samples to improve experimental performance and data quality.
• Operate laboratory instruments including flow cytometers (FACS), cell counters, PCR/qPCR systems, and other molecular biology equipment.
• Analyze experimental results, maintain accurate laboratory records, prepare reports, and communicate findings with internal teams and customers when required.
• Troubleshoot experimental issues, improve laboratory workflows, and contribute to the development and validation of single-cell methodologies.
• Collaborate with research teams and support the training or supervision of junior team members when needed.

Requirements

• A Master’s degree with 1–3 years of relevant hands‑on laboratory experience.
• Hands‑on experience with single‑cell sequencing platforms (10x Genomics or equivalent) and related experimental workflows.

Experience in

• Single‑cell suspension preparation and tissue dissociation (human/mouse tissues)
• Flow cytometry/FACS operation
• Molecular biology techniques including PCR, qPCR, purification, and NGS workflows
• Experience with protocol optimization, troubleshooting, and laboratory SOPs.
• Familiarity with organoids, recombinant AAV, screening, or low‑input molecular assays is a plus.
• Basic experience with data analysis tools (e.g., Prism, Spotfire, or equivalent) and interest in bioinformatics is preferred.
• Good communication skills and ability to work collaboratively in a research environment.
• Willingness to travel when required.
• Proficiency in English (written and spoken).