Senior AI Full‑Stack Engineer – Genomics & LLM

SOPHiA GENETICS; Genf; Hybrid; CHF 73,000 - 139,000; Full time

Benefits offered by this job

Health insurance

Meal vouchers

Free coffee & snacks

Free parking

Leadership exposure

Job summary

SOPHiA GENETICS is seeking a Senior AI Software Engineer to strengthen our Engineering Hub, delivering full-stack web features and microservices for a globally distributed platform that connects hospitals and labs. You will lead AI-powered enhancements and hands-on LLM applications, including RAG pipelines and citations for clinical interpreters.

You will mentor engineers, ship end-to-end components, and collaborate across teams to meet regulatory needs in a hybrid work setup (3 days onsite in

Qualifications

• 5–7 years building and releasing reliable web-based services to production.

Responsibilities

• Design, build, test, deploy and maintain full-stack web features and microservices, owning components end to end.
• Lead code and design reviews; mentor junior engineers and raise the team's engineering quality.
• Prototype fast and iterate — take early ideas to working, reliable software.
• Collaborate with Product, QA, Architecture and PMO to align delivery with product vision and regulatory needs.
• Build retrieval-augmented generation (RAG) pipelines over curated clinical data sources and internal databases.
• Design system and task-specific prompts, structured output, and provenance/citation handling.
• Build LLM evaluation into the product: graders and evaluation pipelines that score accuracy, relevance and grounding, plus guardrails that verify citations resolve and are relevant.
• Use managed LLM endpoints on Azure AI Foundry effectively (caching, tools, structured output), and share these practices with the team.

Skills

Java

SQL

React

JavaScript

Docker

Kubernetes

CI/CD

LLM

RAG pipelines

AI tooling

Mentoring

Communication

Education

Bachelor's degree in Computer Science / Engineering

Tools

Azure AI Foundry

GraphQL

Grafana

Loki

Job description

SOPHiA GENETICS is seeking a Senior AI Software Engineer to strengthen our Engineering Hub, delivering full-stack web features and microservices for a globally distributed platform that connects hospitals and labs. You will lead AI-powered enhancements and hands-on LLM applications, including RAG pipelines and citations for clinical interpreters.

You will mentor engineers, ship end-to-end components, and collaborate across teams to meet regulatory needs in a hybrid work setup (3 days onsite in