Senior AI Full-Stack Engineer for Genomics (Hybrid)

SOPHiA GENETICS; Rolle; Hybrid; CHF 73,000 - 139,000; Full time

Benefits offered by this job

Health insurance

Meal vouchers

Free coffee and snacks

Job summary

SOPHiA GENETICS seeks a Senior AI Software Engineer to join its Engineering Hub. You’ll ship full‑stack features and lead hands‑on production LLM projects, drafting evidence‑grounded gene descriptions and citations for clinical interpreters.

You’ll mentor engineers, drive rapid prototyping, and collaborate across Product, QA, Architecture and PMO to meet regulatory needs. Hybrid work is offered with multiple global locations.

Qualifications

• 5–7 years building and releasing reliable web-based services to production.
• Back-end: strong Java and SQL, microservice architecture. Front-end: React and modern JavaScript.
• Containerization and orchestration (Docker, Kubernetes) and CI/CD.
• Hands-on experience with production LLM applications — specifically RAG pipelines and/or LLM evaluation — OR clear, demonstrable evidence of rapidly self-learning new technical areas to production quality.
• Experience using AI tooling in the SDLC (AI-assisted coding, review, documentation).
• Strong communication and a real appetite for mentoring.
• Bachelor's degree in Computer Science / Engineering, or equivalent professional experience.

Responsibilities

• Design, build, test, deploy and maintain full-stack web features and microservices, owning components end to end.
• Lead code and design reviews; mentor junior engineers and raise the team's engineering quality.
• Prototype fast and iterate — take early ideas to working, reliable software.
• Collaborate with Product, QA, Architecture and PMO to align delivery with product vision and regulatory needs
• Build retrieval-augmented generation (RAG) pipelines over curated clinical data sources and internal databases.
• Design system and task-specific prompts, structured output, and provenance/citation handling.
• Build LLM evaluation into the product: graders and evaluation pipelines that score accuracy, relevance and grounding, plus guardrails that verify citations resolve and are relevant.
• Use managed LLM endpoints on Azure AI Foundry effectively (caching, tools, structured output), and share these practices with the team.

Skills

Java

SQL

React

JavaScript

CI/CD

Mentoring

Communication

English

Education

Bachelor's degree in Computer Science / Engineering

Tools

Docker

Kubernetes

Azure AI Foundry

Grafana

Loki

GraphQL

Job description

SOPHiA GENETICS seeks a Senior AI Software Engineer to join its Engineering Hub. You’ll ship full‑stack features and lead hands‑on production LLM projects, drafting evidence‑grounded gene descriptions and citations for clinical interpreters.

You’ll mentor engineers, drive rapid prototyping, and collaborate across Product, QA, Architecture and PMO to meet regulatory needs. Hybrid work is offered with multiple global locations.