Medical Scientist

Proclinical; Schweiz; Vor Ort; CHF 180.000 - 240.000; Vollzeit

Zusammenfassung

Proclinical is recruiting a Principal Scientist in Immunology to lead breakthrough work in inflammation and biologics discovery. You will shape therapeutic approaches from target identification to preclinical development and mentor a talented team of scientists.

You will oversee multidisciplinary programmes spanning target identification, pharmacology, translational research and antibody development, combining hands-on science with leadership to advance novel therapies.

Qualifikationen

• PhD in Immunology or related field with 5+ years in inflammation or biologics.
• Strong leadership and mentoring experience in scientific teams.
• Proven record in publishing peer-reviewed work.
• Experience leading target identification to preclinical programs.
• Experience with CROs and external partners.
• Excellent communication and strategic thinking.

Aufgaben

• Lead and mentor a team of scientists and drive scientific delivery.
• Design and interpret in vitro and in vivo pharmacology studies.
• Advance autoimmune and inflammatory disease programs.
• Develop immune-based assays for target validation and antibody discovery.
• Collaborate across immunology, translational medicine, protein engineering, biomarkers and clinical development.
• Coordinate efficacy and pharmacology studies with CROs.
• Implement endpoint and mechanism-of-action studies, including ex vivo profiling.
• Identify project risks and influence strategy.
• Contribute to publications, patents, regulatory docs and due diligence.
• Represent programmes at conferences and collaborations.

Kenntnisse

Immunology leadership

Biologics discovery

In vivo pharmacology

In vitro pharmacology

Assay development

Target validation

Team mentoring

Regulatory documentation

Scientific publications

CRO management

Ausbildung

PhD in Immunology

Jobbeschreibung

Are you a highly accomplished Immunologist with a track record of leading scientific teams and driving biologics discovery programmes in autoimmune and inflammatory diseases?
Proclinical is recruiting for a Principal Scientist, this position will oversee breakthrough work in inflammation and immunology. You'll play a central role in shaping therapeutic approaches, developing next-generation biologic therapies, mentoring talented scientists, and advancing programs from target identification to preclinical development.

Working at the forefront of immunology research, you will lead and support multidisciplinary programmes spanning target identification, pharmacology, translational research and therapeutic antibody development. You will combine hands-on scientific expertise with leadership, helping to advance novel biologic therapies from early discovery through preclinical development.

Responsibilities:

• Lead and mentor a team of laboratory-based scientists, supporting both scientific delivery and career development
• Design, oversee and interpret complex in vitro and in vivo pharmacology studies
• Drive the development of novel therapeutic strategies within autoimmune and inflammatory disease programmes
• Design and optimise immune-based assays to support target validation and antibody discovery
• Collaborate closely with experts across immunology, translational medicine, protein engineering, biomarkers and clinical development
• Work with CRO partners to coordinate efficacy and pharmacology studies
• Develop and implement endpoint and mechanism-of-action studies, including ex vivo immune profiling
• Identify project risks, influence programme strategy and support key decision-making discussions
• Contribute to scientific publications, patents, regulatory documentation and due diligence activities
• Represent research programmes through conference presentations and external scientific collaborations

Key Skills and Requirements:

• PhD in Immunology, Life Sciences or a related discipline
• Minimum 5 years' experience within immunology, inflammation research or biologics drug discovery
• Strong understanding of autoimmune disease biology and immune system mechanisms
• Proven experience leading scientific projects and mentoring research teams
• Expertise across in vitro pharmacology, assay development and immune profiling
• Experience supporting biologics, antibody or therapeutic development programmes
• Strong publication record with peer-reviewed scientific contributions
• Excellent communication, stakeholder management and leadership skills
• Biotechnology or pharmaceutical industry experience
• In vivo pharmacology programme leadership
• Translational research and target validation experience
• Experience working with CROs and external research partners
• Contribution to IND-enabling studies, patent applications or due diligence activities
• Exposure to strategic portfolio or pipeline decision-making