Molecular Pathologist (80 – 100%), Novartis Pharma AG, Basel, Switzerland

European Society of Veterinary Pathology; Basel; Vor Ort; CHF 180.000 - 240.000; Vollzeit

Zusammenfassung

The Novartis Institutes for Biomedical Research (NIBR) ATI group seeks an innovative Molecular Pathologist to lead an experimental pathology lab within the Translational Research group. You will guide pathology strategy and collaborate with multidisciplinary teams to advance immunological targets and biomarkers.

MD or DVM with PhD-level research and board-certified pathology expertise are essential, with strong leadership and communication skills in English; German desirable.

Qualifikationen

• MD or DVM with relevant human pathology experience; plus PhD-level research background
• Board-certified Pathologist
• Excellent oral and written communication skills in English, German desirable
• Strong Experimental Pathology background/expertise
• Training and interest in Autoimmune and Dermatological Diseases highly desirable
• Experience in animal mechanistic and disease models as well as human biosamples
• Strong background and expertise in immunohistochemistry, in-situ hybridization, immunoflourescence and confocal microscopy, laser capture microdissection, automated digital slide scanning systems and quantitative digital image analysis software
• Strong leadership skills – experienced line management, development of team members and retention of high performers
• Excellent presentation and communication skills, innovative thinking and project management skills

Aufgaben

• Use samples from animal models and human tissues to study integrated biology of immunological pathways
• Develop pharmacodynamics endpoints of pharmacological intervention
• Use imaging modalities such as confocal microscopy, laser capture microdissection and digital image quantification to address key scientific questions
• Provide pathology expertise for clinical proof of concept studies
• Work closely with multidisciplinary project teams in discovery and translational research

Kenntnisse

Experimental pathology

Leadership

Oral and written communication

Project management

English language proficiency

Ausbildung

MD or DVM with PhD-level research background

Tools

Immunohistochemistry

In-situ hybridization

Immunofluorescence

Confocal microscopy

Laser capture microdissection

Digital image analysis software

Digital slide scanning systems

Jobbeschreibung

1 out of 10 people are diagnosed with an autoimmune or autoinflammatory disease. This is why the Autoimmunity, Transplantation & Inflammation (ATI) Disease Area group at the Novartis Institutes for Biomedical Research (NIBR) is investing in the discovery of innovative and transformative therapies to improve the life of affected patients. As part of this effort, ATI is seeking an innovative and highly motivated Molecular Pathologist, who will lead an experimental pathology lab within the Translational Research group within ATI.

Your responsibilities will include

• Use samples from animal models and from healthy and diseased human tissues to
  • Further our understanding of the integrated biology of immunological pathways
  • Validate these pathways as pharmacological targets in immunologically mediated diseases
  • Develop mechanism- and pathway-based biomarkers of disease
• Develop pharmacodynamics endpoints of pharmacological intervention
• Use of state-of-the-art imaging modalities such as confocal microscopy, laser capture microdissection and digital image quantification to address key scientific questions
• Provide pathology expertise for clinical proof of concept studies
• Work closely with multidisciplinary project teams in discovery and translational research

What you’ll bring to the role:

• MD or DVM with relevant human pathology experience; plus PhD-level research background
• Board-certified Pathologist
• Excellent oral and written communication skills in English, German desirable
• Strong Experimental Pathology background/expertise
• Training and interest in Autoimmune and Dermatological Diseases highly desirable
• Experience in animal mechanistic and disease models as well as human biosamples
• Strong background and expertise in immunohistochemistry, in-situ hybridization, immunoflourescence and confocal microscopy, laser capture microdissection, automated digital slide scanning systems and quantitative digital image analysis software
• Strong leadership skills – experienced line management, development of team members and retention of high performers
• Excellent presentation and communication skills, innovative thinking and project management skills