Experienced Discovery Scientist in Immunology

Roche; Basel; On-site; CHF 180,000 - 240,000; Full time

Job summary

Roche is seeking a visionary Discovery Scientist to lead immunology-focused efforts within pRED CMI2. You will guide target discovery and validation for inflammatory diseases, oversee preclinical studies, and drive cross-functional programs from discovery through IND-enabling stages.

You will manage a multidisciplinary team of scientists, collaborate with external partners, and mentor researchers to advance innovative cancer/immune disease therapies and translational strategies within a

Qualifications

• PhD in Life Sciences with >10 years in pharma/biotech.
• Proven leadership of multidisciplinary teams in drug discovery.
• Strong publication record in high-impact journals.
• Excellent communication of complex data to diverse audiences.

Responsibilities

• Define and execute scientific strategy for target identification in inflammatory diseases.
• Lead cross-functional teams from discovery to IND-enabling stages.
• Oversee preclinical studies for target validation and translational research.
• Evaluate external licensing opportunities and collaborations, present findings to leadership.
• Mentor and develop scientists to foster collaboration and scientific rigor.

Skills

Scientific leadership

Team mentoring

Strategic thinking

Communication

Education

PhD in Life Sciences

Job description

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

In Roche’s Pharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility, and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.

The Opportunity

To complement the Immunology team in pRED CMI2, we are seeking a visionary, strategic, experienced Discovery Scientist with a strong academic background in inflammation research, a track record in drug discovery from target discovery to Ph1 and proven ability to effectively lead teams and projects.

As an experienced DiscoveryScientist in pRED CMI2, you will be a core scientific leader of an international and multidisciplinary group of scientists and clinicians committed to delivering innovative solutions for patients living with IBD, COPD and other inflammatory diseases by combining cutting-edge approaches in biology, pharmacology and translational research.

Key Responsibilities:

• Scientific leadership and strategy: define and execute the scientific strategy for novel target identification and validation in inflammatory diseases
• Project leadership: lead cross-functional teams to drive pipeline programs from early discovery to IND-enabling stages
• Subject matter leadership: with our dedicated team of lab-based associates and post-doctoral scientists, you will direct, oversee and interpret complex preclinical experimental studies for the validation and characterisation of targets or therapeutic approaches
• External representation and partnerships: As an internal expert in evaluating external licensing opportunities and academic collaborations, you will be a member of diligence teams and present the findings to leadership
• Mentorship and development: Managing, mentoring and developing scientists and postdocs to foster a culture of collaboration, innovation, and scientific rigor

Who You Are

• You hold a PhD degree in Life Sciences (cellular/ molecular biology, pharmacology, immunology - or closely related field) and bring >10 years of experience in the pharmaceutical industry.
• You bring deep expertise in disease biology of inflammatory diseases, including inflammatory bowel disease and/or chronic obstructive pulmonary disease
• You have led drug discovery projects in the pharmaceutical / biotech industry and collaborated on in- or out-licensing activities. You have a good understanding of pharmacological properties of therapeutic modalities such as small molecules and antibodies.
• You have significant scientific accomplishments and successful collaborations documented by publications in high-impact journals
• You value collaboration within and across teams and have a strong visionary and strategic thinking capacity. You integrate clinical and commercial aspects into early drug discovery strategies and you have the ability to balance multiple priorities in a fast-paced, matrixed organisation.
• You are a proficient communicator of scientific data and strategic concepts to colleagues, teams and senior management.

At Roche, we aim high to deliver life-changing healthcare solutions. If you’re ready to make a meaningful impact on patients and healthcare systems worldwide, this is the place for you.

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an Equal Opportunity Employer.