Experienced Discovery Scientist in Immunology

F. Hoffmann-La Roche AG; Basel; On-site; CHF 250,000 - 350,000; Full time

Job summary

Roche’s Immunology team in pRED focuses on identifying and developing innovative treatments for inflammatory diseases. You will lead strategy and cross-functional teams to advance targets from discovery to IND-enabling stages, guiding preclinical studies and external collaborations.

The role requires a PhD in Life Sciences with 10+ years in pharma, strong leadership, and ability to balance multiple priorities in a fast-paced, matrixed organization.

Qualifications

• PhD in Life Sciences with >10 years in pharma/biotech.
• Deep disease biology expertise in inflammatory diseases.
• Proven drug discovery leadership and cross-functional collaboration.
• Strong publications in high-impact journals.

Responsibilities

• Define and execute the scientific strategy for target identification and validation in inflammatory diseases.
• Lead cross-functional teams to drive pipeline programs from discovery to IND-enabling stages.
• Direct, oversee and interpret preclinical studies for target validation and characterization.
• Evaluate external licensing opportunities and collaborations and present findings to leadership.
• Mentor and develop scientists and postdocs to foster collaboration and scientific rigor.

Skills

Leadership

Communication

Mentorship

Strategic thinking

Cross-functional collaboration

Education

PhD in Life Sciences

Job description

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position In Roche’s Pharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility, and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed. In the Immunology Department of pRED’s Cardiovascular, Metabolism, Immunology, Infectious Diseases (CMI2), we focus on the discovery and early development of innovative treatments for inflammatory diseases that affect the lives of millions.

Key Responsibilities

• Scientific leadership and strategy: define and execute the scientific strategy for novel target identification and validation in inflammatory diseases
• Project leadership: lead cross-functional teams to drive pipeline programs from early discovery to IND-enabling stages
• Subject matter leadership: with our dedicated team of lab-based associates and post-doctoral scientists, you will direct, oversee and interpret complex preclinical experimental studies for the validation and characterisation of targets or therapeutic approaches
• External representation and partnerships: As an internal expert in evaluating external licensing opportunities and academic collaborations, you will be a member of diligence teams and present the findings to leadership
• Mentorship and development: Managing, mentoring and developing scientists and postdocs to foster a culture of collaboration, innovation, and scientific rigor

Who You Are

• You hold a PhD degree in Life Sciences (cellular/ molecular biology, pharmacology, immunology - or closely related field) and bring >10 years of experience in the pharmaceutical industry
• You bring deep expertise in disease biology of inflammatory diseases, including inflammatory bowel disease and/or chronic obstructive pulmonary disease
• You have led drug discovery projects in the pharmaceutical / biotech industry and collaborated on in- or out-licensing activities
• You have a good understanding of pharmacological properties of therapeutic modalities such as small molecules and antibodies
• You have significant scientific accomplishments and successful collaborations documented by publications in high-impact journals
• You value collaboration within and across teams and have a strong visionary and strategic thinking capacity
• You integrate clinical and commercial aspects into early drug discovery strategies and you have the ability to balance multiple priorities in a fast-paced, matrixed organisation
• You are a proficient communicator of scientific data and strategic concepts to colleagues, teams and senior management

At Roche, we aim high to deliver life-changing healthcare solutions. If you’re ready to make a meaningful impact on patients and healthcare systems worldwide, this is the place for you.

Who we are A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let’s build a healthier future, together. Roche is an Equal Opportunity Employer. We believe it’s urgent to deliver medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients’ lives. We are courageous in both decision and action. And we believe that good business means a better world. That is why we come to work each day. We commit ourselves to scientific rigor, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow. We are proud of who we are, what we do, and how we do it. We are many, working as one across functions, across companies, and across the world. We are Roche.