Global Clinical Site Management Excellence Lead

Merck; Eysins; On-site; CHF 180,000 - 260,000; Full time

Job summary

Merck in Switzerland, Eysins, is seeking a Clinical Site Management Excellence Lead to drive global harmonization of monitoring and site management. You will partner with regional and global teams to design scalable, compliant processes enabling effective trial execution, including risk-based monitoring and digital tool integration.

You will lead end-to-end clinical processes and oversee performance across global environments, ensuring ICH-GCP compliance and a data-driven approach.

Qualifications

• Advanced degree in Life Sciences, Medicine, Clinical Research, or related field or equivalent experience.
• 12+ years in clinical research with site management and clinical monitoring across global environments.
• Proven track record owning end-to-end clinical processes, including design, documentation, performance oversight, and improvement in a regulated setting.
• Deep knowledge of ICH-GCP guidelines, including ICH E6(R3), with Quality by Design and risk-based quality management principles.
• Led cross-functional initiatives in complex matrix organizations, aligning CROs and vendors without direct authority.
• Partnered with technology and digital teams to shape system requirements and drive adoption of tools that support compliance and operational efficiency.
• Strong analytical and data-driven approach to translate performance metrics into targeted improvements.
• Comfortable in a global, multicultural setting and willing to travel internationally up to 20%.

Responsibilities

• Drive excellence in the planning, execution, and oversight of clinical trial monitoring and site management.
• Global harmonization of monitoring practices, ensuring inspection-readiness and regulatory compliance.
• Define site activation, initiation, monitoring, escalation, CAPA linkage, and close-out processes.
• Coordinate interactions with country, regional, and global levels, CROs, vendors, and cross-functional study teams.
• Partner with regional heads and study teams to design scalable, efficient processes that align with GDO and R&D objectives.
• Act as an internal transformation consultant to implement compliant, scalable workflows.

Skills

Clinical site management

Clinical monitoring

Quality by Design

ICH-GCP

Cross-functional leadership

Data-driven decisions

Global collaboration

Travel willingness

Education

Advanced degree in Life Sciences / Medicine / Clinical Research

Job description

Merck in Switzerland, Eysins, is seeking a Clinical Site Management Excellence Lead to drive global harmonization of monitoring and site management. You will partner with regional and global teams to design scalable, compliant processes enabling effective trial execution, including risk-based monitoring and digital tool integration.

You will lead end-to-end clinical processes and oversee performance across global environments, ensuring ICH-GCP compliance and a data-driven approach.