Cryo-EM Specialist: SPA, Cryo-ET & Image Processing

École polytechnique fédérale de Lausanne, EPFL; Lausanne; On-site; CHF 110,000 - 140,000; Full time

Job summary

EPFL, the Swiss Federal Institute of Technology in Lausanne, invites applications for a Cryogenic Electron Microscopist to support the Dubochet Center for Imaging (DCI). The role involves operating and maintaining high-end cryo-EM instruments, providing user training and expert data analysis for SPA and cryo-ET, and contributing to platform development in a dynamic, international environment.

You will collaborate with researchers from EPFL and UNIL, and with external customers, ensuring

Qualifications

• Ph.D. in structural biology or related field with experience in Cryo-EM.
• At least one year of hands-on experience in cryo-EM, including instrument operation, facility support, training, data acquisition, data processing and/or cryo-ET
• Experience with cryo-EM image-processing software such as cryoSPARC, IMOD/eTomo, and Scipion
• Experience with SPA and/or cryo-ET workflows is desirable
• Good understanding of cryo-EM data acquisition and processing workflows
• Excellent communication skills in an English-speaking environment
• Strong motivation to explore new research domains

Responsibilities

• Data acquisition for single-particle analysis (SPA) and cryo-electron tomography (cryo-ET)
• On-the-fly and offline data processing, advanced image processing
• Structure determination and interpretation
• As a cryo-EM support, you will provide technical and scientific support to researchers from EPFL, UNIL as well as external customers, advising users throughout the different stages of their projects, from experimental planning and data acquisition to image processing and structure determination. You will also contribute to the continuous development and improvement of the DCI cryo-EM platform, helping to ensure a high level of service, reliability and performance for its users.

Skills

Excellent communication in English

Service-oriented

Hands-on and practical

Team collaboration

Education

Ph.D. in structural biology or related field

Tools

cryoSPARC

IMOD/eTomo

Scipion

Job description

EPFL, the Swiss Federal Institute of Technology in Lausanne, invites applications for a Cryogenic Electron Microscopist to support the Dubochet Center for Imaging (DCI). The role involves operating and maintaining high-end cryo-EM instruments, providing user training and expert data analysis for SPA and cryo-ET, and contributing to platform development in a dynamic, international environment.

You will collaborate with researchers from EPFL and UNIL, and with external customers, ensuring