Cryogenic Electron Microscopist support for the Dubochet Center for Imaging

EPFL; Lausanne; Vor Ort; CHF 100.000 - 140.000; Vollzeit

Benefits dieser Stelle

Competitive salary

Access to high-end instrumentation

Zusammenfassung

EPFL's Dubochet Center for Imaging in Lausanne seeks a Cryogenic Electron Microscopist to operate, maintain and troubleshoot the Glacios and three Titan Krios microscopes within the cryo-EM core facility. You will support researchers from EPFL/UNIL and external customers, contributing to platform development and high-level service.

The role advances data acquisition, processing and structure determination workflows, with collaboration across an international team in a dynamic research

Qualifikationen

• Ph.D. in structural biology or related field with cryo-EM experience.
• At least 1 year hands-on cryo-EM experience including operation, support, training, data acquisition or cryo-ET.
• Experience with cryo-EM software such as cryoSPARC, IMOD/eTomo and Scipion.
• SPA and/or cryo-ET workflows desirable.
• Strong understanding of cryo-EM data acquisition and processing workflows.
• Excellent communication skills in an English-speaking environment.
• Strong motivation to explore new research domains.

Aufgaben

• Cryo-EM sample preparation.
• Data acquisition for SPA and cryo-ET.
• On-the-fly and offline data processing, advanced image processing.
• Structure determination and interpretation.
• Provide technical and scientific support to researchers from EPFL, UNIL and external customers.

Kenntnisse

Cryo-EM expertise

Cryo-EM hands-on

Cryo-EM software

SPA/Cryo-ET workflows

Data acquisition/processing

English communication

Adaptability

Ausbildung

Ph.D. in structural biology or related field

Tools

cryoSPARC

IMOD/eTomo

Scipion

Jobbeschreibung

Mission

The Cryogenic Electron Microscopist will be responsible for the operation, maintenance and troubleshooting of specialized scientific equipment, including one Glacios and three Titan Krios microscopes, within the cryo-EM core facility of the Dubochet Center for Imaging (DCI).

Main Duties And Responsibilities

As part of the DCI team, your responsibilities will include:

• Cryo-EM sample preparation
• Data acquisition for single-particle analysis (SPA) and cryo-electron tomography (cryo-ET)
• On-the-fly and offline data processing, advanced image processing
• Structure determination and interpretation

As a cryo-EM support, you will provide technical and scientific support to researchers from EPFL, UNIL as well as external customers, advising users throughout the different stages of their projects, from experimental planning and data acquisition to image processing and structure determination. You will also contribute to the continuous development and improvement of the DCI cryo-EM platform, helping to ensure a high level of service, reliability and performance for its users.

Profile

• Ph.D. in tructural biology or related field with experience in Cryo-EM
• At least one year of hands-on experience in cryo-EM, including instrument operation, facility support, training, data acquisition, data processing and/or cryo-ET
• Experience with cryo-EM image-processing software such as cryoSPARC, IMOD/eTomo, and Scipion
• Experience with SPA and/or cryo-ET workflows is desirable
• Good understanding of cryo-EM data acquisition and processing workflows
• Excellent communication skills in an English-speaking environment
• Strong motivation to explore new research domains

We Are Looking For a Person Who Is

• Service-oriented, proactive, and enthusiastic
• Practical and hands-on, with the flexibility to thrive in a dynamic, service-oriented platform
• Comfortable with change and able to adapt quickly to evolving priorities and workflows
• Reliable and committed to delivering high-quality results for all types of users and customers
• Collaborative, with clear communication skills and a constructive team spirit
• Able to work independently while contributing effectively to a team environment

We offer

The position is based in the campus of EPFL and UNIL in Lausanne, Switzerland, and is available from 01 January 2027. It will initially be offered as a one-year contract, with the possibility of renewal. The position offers a competitive salary.

EPFL as well as UNIL are committed to being an equal opportunity employer.

The Dubochet Center is currently equipped with three 300 kV Titan Krios with Cold-FEG and Falcon 4i direct electron detectors, and a Glacios 200 kV microscope. You will join a collaborative, international, and diverse research team from UNIL and EPLF with interdisciplinary expertise in biology, physics, computer science, and engineering.

For more information about the Dubochet Center please visit our website: https://dci-lausanne.ch/.

Contract Start Date : 01/01/2027

Activity Rate : 100.00

Contract Type: CDD

Duration: 1 an

Reference: 2495