Research Assistant – University of Saskatchewan

Canadian Association for Neuroscience; Saskatoon; On-site; CAD 65,000 - 103,000; Full time

Job summary

Join a dynamic research team focused on neurodegeneration and multiple sclerosis. This role offers the opportunity to work with cutting-edge technologies and contribute to groundbreaking research. As a research assistant, you'll engage in various molecular biology techniques, conduct in vitro and in vivo experiments, and support the development of small molecules aimed at neuroprotection. Collaborating with a world-class team, you'll enhance your skills in a supportive environment that values diversity and inclusion. This is a unique chance to make a significant impact in the field of neuroscience while advancing your career in a vibrant academic setting.

Qualifications

• 3-5 years of experience in molecular biology or neuroscience.
• Experience with mouse models and cell culture.
• Proven publication record and mentoring experience.

Responsibilities

• Design and conduct research on MS and neurological diseases.
• Document experiments, analyze data, and contribute to publications.
• Train and supervise trainees at all levels.

Skills

Immunohistochemistry

Microscopy

Molecular Techniques

Small Animal Procedures

Bioinformatics

Statistical Software

Communication Skills

Organizational Skills

Leadership Skills

Education

Graduate degree (PhD preferred, MSc acceptable) in molecular biology, neuroscience, or related field

Tools

PCR/qPCR

Molecular Cloning

Sequencing

Data Analysis Software

Job description

Join a dynamic, world-class research team led by Dr. Michael Levin, the Saskatchewan Multiple Sclerosis Clinical Research Chair.

Our team focuses on neurodegeneration, studying neuron death and damage as major causes of disability in MS and other neurological diseases. We utilize computer modeling, molecular, and imaging technologies to develop small molecules that inhibit neurodegeneration and promote neuroprotection in vitro and in small animal models.

We seek a research assistant with a strong background in molecular neurobiology, experience with primary mouse neurons, human IPSCs, small animal handling, and molecular biology techniques (RNA/DNA isolation, RNAseq, AAVs, single-cell isolation and sequencing). The role involves testing small molecules for potential clinical trials. Led by Dr. Levin, you can learn more about our work via our TED Talk, lab website, and recent publications linked in the original description.

Key Responsibilities:

1. Design, conduct, and support research on MS and neurological diseases, including neuroimmunology, neuroscience, immunology, molecular biology, bioinformatics, and biostatistics.
2. Report regularly to the SK MS Research Chair, plan projects, and meet deadlines.
3. Document experiments, analyze data, and contribute to scientific publications.
4. Train and supervise trainees at all levels.
5. Assist in grant writing and manuscript preparation.

Typical Duties:

1. Perform and optimize in vitro experiments with cell lines, primary neurons, and human IPSCs.
2. Maintain detailed laboratory notebooks.
3. Transfect and transduce cell lines and primary neurons.
4. Conduct in vivo experiments using mouse and rat models of MS.
5. Work with human tissue samples using immunohistochemistry and immunofluorescence.
6. Develop and improve experimental protocols.
7. Present findings at meetings and assist with publications.
8. Train and mentor trainees, establish SOPs.

Qualifications:

• Graduate degree (PhD preferred, MSc acceptable) in molecular biology, neuroscience, or related field with 3-5 years of experience.
• Experience with mouse models, cell culture, imaging, protein analysis, PCR/qPCR, molecular cloning, sequencing, and human tissue analysis.
• Proficiency in bioinformatics and data analysis software.
• Experience mentoring junior researchers and a proven publication record.

Skills:

• Immunohistochemistry, microscopy, molecular techniques.
• Small animal procedures.
• Computer skills including bioinformatics and statistical software.
• Excellent communication, organizational, and leadership skills.

Details:

Department: Medicine
Status: Term, 1-year
FTE: 1.0
Salary: $65,975–$102,024/year, commensurate with experience.
Location: On campus, Saskatoon, Saskatchewan, Canada.

We support diversity, equity, and inclusion, especially Indigenous employment, and provide accommodations for applicants with disabilities. Candidates must be eligible to work in Canada.