Production Supervisor

Jobat; Zwijnaarde; Sur place; EUR 55 000 - 75 000; Plein temps

Résumé du poste

Legend Biotech in Zwijnaarde is seeking a Production Supervisor to manage the daily production process of personalized cell therapy for clinical and commercial purposes. You will lead various operational units within the CAR‑T production process, ensuring compliance with cGMP requirements and facilitating smooth cross-team collaboration.

Ideal candidates will demonstrate strong leadership abilities, an understanding of quality activities, and a commitment to process improvements. Join a team dedicated to making a difference in the lives of patients facing life-threatening diseases.

Qualifications

• Strong understanding of cGMP requirements and quality standards.
• Experience in biotechnology or cell therapy production.
• Demonstrated leadership capability in operational environments.

Responsabilités

• Lead and supervise operational units within the CAR‑T production process.
• Act as the primary point of contact for production‑related topics.
• Provide hands‑on leadership on the shop floor.

Description du poste

Our client, Legend Biotech, based in Zwijnaarde, is a global biotechnology company bringing the innovative CAR‑T cell therapy to Ghent. With this, the Legend Biotech team makes a daily difference in the lives of many patients suffering from cancer and other life‑threatening diseases.

They are currently in a phase of strong growth and are looking for motivated and dedicated team members.

Jobomschrijving

As a Production Supervisor, you are responsible for the daily production process of personalized cell therapy, both for clinical and commercial purposes. You will lead various units within the CAR‑T process and ensure safe and compliant production activities in accordance with cGMP requirements — all while coordinating and overseeing operations from your dedicated office workspace, maintaining a clear overview of the production floor and ensuring smooth cross‑team collaboration.

Tasks

• Lead and supervise operational units within the CAR‑T production process, including component preparation, production support, CAR‑T processing, filling & finishing, and cryopreservation.
• Act as the primary point of contact for production‑related topics, ensuring smooth coordination with Manufacturing Operations, QC IPC, Quality, Facilities & Engineering, MS&T/Manufacturing Excellence, Training, Planning, and Supply Chain.
• Provide hands‑on leadership on the shop floor, supporting teams in daily operations, troubleshooting, and decision‑making in cGMP environments.
• Serve as a subject matter expert for Quality and Operations and play a key role during GMP inspections and external audits.
• Oversee production quality activities, including documentation management (procedures, work instructions, logs, transfer forms), batch record review and release, and compliance with cGMP standards.
• Coordinate quality system processes such as Change Controls, Deviations/Events, and CAPA.
• Guide and support team development through structured training and operational coaching.
• Drive operational excellence by leading process improvements focused on efficiency, cost reduction, and quality enhancement.