MSAT Process Engineer

Arcadis; Geel; Sur place; EUR 60 000 - 90 000; Plein temps

Résumé du poste

Arcadis in Geel, Belgium, is seeking an MSAT scientist to support technology transfer of new drug substances and process optimization for manufacturing scale. You will collaborate with development labs and the manufacturing site to ensure smooth transitions and robust, cost-effective methods.

The role requires a Life Sciences PhD or Master’s with relevant MSAT experience, fluent English, and hands-on mammalian cell culture or purification at lab or manufacturing scale. GMP knowledge is a plus.

Qualifications

• PhD or Master’s degree in Life Sciences with a minimum of 3 years (PhD) or 5 years (Master’s) relevant experience in process development or MSAT-like roles.
• Fluent in oral and written English to effectively operate in an international environment.
• Hands-on experience with mammalian cell culture or purification processes at laboratory and/or manufacturing scale.
• Flexibility: willingness to adapt to dynamic work demands, including occasional evening or weekend shifts, and supporting both small-scale lab studies and manufacturing-scale operations.
• A team player who works effectively across multidisciplinary teams and fosters productive relationships.
• Ability to adjust to shifting priorities in a fast-paced environment.
• Strong interpersonal skills to connect with colleagues, facilitate discussions, and negotiate compromises with other departments or sites.
• A precise, detail-oriented mindset with excellent analytical skills for identifying and addressing challenges.
• Familiarity with statistical and data trending techniques; experience with tools like JMP, Statistica, Matlab, or Simca is a plus.
• A solid understanding of current Good Manufacturing Practices (GMP); prior GMP experience is an asset.

Responsabilités

• Support the introduction of new drug substance manufacturing processes by facilitating the technology transfer from development laboratories to large-scale GMP manufacturing facilities. This includes ensuring documentation readiness (e.g., conducting process fit-gap analyses, defining process control strategies, preparing media batch sheets and sampling plans) for clinical batch production, as well as providing support during process performance qualification to successfully implement new processes at manufacturing scale.
• Identify and lead process improvement initiatives to increase process yield or robustness, and generate supportive data packages to enable implementation at manufacturing scale.
• Provide ongoing support for existing commercial manufacturing processes through activities such as data trending and monitoring, developing scientific and technical study protocols and reports to support significant process changes, and contributing to investigations and process/product impact assessments for significant manufacturing deviations.

Connaissances

English fluency

Mammalian cell culture

Purification processes

Data analysis

Teamwork

Interpersonal skills

Analytical skills

Formation

Life Sciences Doctorate (PhD)

Life Sciences Master’s degree

Outils

JMP

Statistica

Matlab

Simca

Description du poste

The Manufacturing Science, Analytical and Technology department (MSAT) represents the scientific backbone of the company that provides commercial manufacturing support, process/method optimization (lifecycle management), technology transfer of new products and processes/methods and development of innovative, robust, and cost-effective next-generation processes/methods.

Leveraging strong scientific and technical knowledge, you will actively contribute to Technology Transfer activities facilitating the introduction of new products and processes at the manufacturing site. Additionally, you will support improvement initiatives and the ongoing monitoring of existing processes, both at the Geel site and within the broader network. The position primarily focuses on cell culture or purification manufacturing-scale activities, but involves a strong collaboration with the laboratory team on laboratory-scale activities.

Tasks

• Support the introduction of new drug substance manufacturing processes by facilitating the technology transfer from development laboratories to large-scale GMP manufacturing facilities. This includes ensuring documentation readiness (e.g., conducting process fit-gap analyses, defining process control strategies, preparing media batch sheets and sampling plans) for clinical batch production, as well as providing support during process performance qualification to successfully implement new processes at manufacturing scale.
• Identify and lead process improvement initiatives to increase process yield or robustness, and generate supportive data packages to enable implementation at manufacturing scale.
• Provide ongoing support for existing commercial manufacturing processes through activities such as data trending and monitoring, developing scientific and technical study protocols and reports to support significant process changes, and contributing to investigations and process/product impact assessments for significant manufacturing deviations.

Skills

• PhD or Master’s degree in Life Sciences with a minimum of 3 years (PhD) or 5 years (Master’s) relevant experience in process development or MSAT-like roles.
• Fluent in oral and written English to effectively operate in an international environment.
• Hands-on experience with mammalian cell culture or purification processes at laboratory and/or manufacturing scale.
• Flexibility: willingness to adapt to dynamic work demands, including occasional evening or weekend shifts, and supporting both small-scale lab studies and manufacturing-scale operations.
• A team player who works effectively across multidisciplinary teams and fosters productive relationships.
• Ability to adjust to shifting priorities in a fast-paced environment.
• Strong interpersonal skills to connect with colleagues, facilitate discussions, and negotiate compromises with other departments or sites.
• A precise, detail-oriented mindset with excellent analytical skills for identifying and addressing challenges.
• Familiarity with statistical and data trending techniques; experience with tools like JMP, Statistica, Matlab, or Simca is a plus.
• A solid understanding of current Good Manufacturing Practices (GMP); prior GMP experience is an asset.