Senior Analytical Development Scientist

Placements24; George; Hybrid; ZAR 900,000 - 1,200,000; Full time

Benefits offered by this job

Health benefits

Retirement plans

Hybrid work model

Professional development

Job summary

Placements24 seeks a Senior Analytical Development Scientist for our George, Western Cape facility. You will lead method development for APIs and finished products, ensuring alignment with GMP standards and regulatory expectations.

You will mentor junior scientists, oversee transfer to QC, and drive analytical strategy, using HPLC/UPLC, spectroscopy, and MS tools, while maintaining rigorous data interpretation.

Qualifications

• Ph.D. or Master's degree in Analytical Chemistry or related field.
• Minimum of 5 years in analytical development within the pharmaceutical industry.
• Extensive hands-on experience with HPLC/UPLC and spectroscopic methods.
• Strong understanding of method validation principles and ICH guidelines.
• Experience with stability studies design and data interpretation.

Responsibilities

• Develop, optimize, and validate analytical methods for APIs and finished products.
• Characterize samples and conduct stability testing per ICH guidelines.
• Troubleshoot instrumentation and method issues.
• Transfer methods to QC labs and provide ongoing support.
• Write method development reports, validation protocols, and validation reports.
• Ensure compliance with GMP and regulatory guidelines.
• Collaborate with formulation, process development, and regulatory teams.
• Stay current with literature and new analytical technologies.
• Manage multiple projects and mentor junior scientists.

Skills

HPLC/UPLC

Spectroscopic methods

Data analysis

Problem solving

Independent work

Education

Ph.D. or Master's in Analytical Chemistry

Tools

LC-MS

GC-MS

Job description

About the Role

Our client, a leading pharmaceutical company dedicated to developing innovative therapies, is seeking a highly skilled Senior Analytical Development Scientist to join their advanced R&D facility in George, Western Cape, ZA . This role is crucial for the development and validation of analytical methods required for the characterization, quality control, and stability testing of pharmaceutical products and active pharmaceutical ingredients (APIs). The ideal candidate will possess extensive expertise in various analytical techniques and a strong understanding of regulatory requirements for pharmaceutical development. You will lead projects, troubleshoot complex analytical challenges, and contribute to the successful transfer of methods to manufacturing and quality control departments. This hybrid role offers a blend of on-site laboratory work in George and flexibility for remote analysis and reporting. We are seeking a meticulous and innovative scientist who is passionate about ensuring the quality and safety of medicines. Your contributions will be vital in supporting our client's pipeline and bringing new treatments to patients. As a Senior Scientist, you will also play a key role in mentoring junior scientists and driving analytical strategy within the department.

Key Responsibilities

• Develop, optimize, and validate analytical methods for APIs and finished pharmaceutical products using techniques such as HPLC, UPLC, GC, KF, dissolution, and spectroscopic methods.
• Perform characterization studies and stability testing according to ICH guidelines.
• Troubleshoot analytical instrumentation and method-related issues.
• Transfer analytical methods to Quality Control (QC) laboratories and provide ongoing support.
• Write detailed method development reports, validation protocols, and validation reports.
• Ensure all analytical activities comply with GMP and relevant regulatory guidelines.
• Collaborate with formulation development, process development, and regulatory affairs teams.
• Stay current with scientific literature, new analytical technologies, and regulatory expectations.
• Manage multiple projects simultaneously and meet project timelines.
• Mentor junior analytical scientists and provide technical guidance.

Requirements

• Ph.D. or Master's degree in Analytical Chemistry, Pharmaceutical Chemistry, or a related scientific discipline.
• Minimum of 5 years of experience in analytical development within the pharmaceutical industry.
• Extensive hands-on experience with a wide range of analytical techniques, particularly HPLC/UPLC and spectroscopic methods.
• Strong understanding of method validation principles and ICH guidelines.
• Experience with stability studies design and data interpretation.
• Proficiency in data analysis and interpretation using relevant software.
• Excellent problem-solving skills and a systematic approach to scientific investigations.
• Strong written and verbal communication skills.
• Ability to work independently and collaboratively in a laboratory environment based in George .
• Experience with Mass Spectrometry (LC-MS, GC-MS) is a plus.

Benefits

Our client offers a competitive salary, comprehensive health and wellness benefits, retirement savings plans, and opportunities for professional development and career advancement.

The hybrid work model provides flexibility, allowing for a balance between on-site laboratory work in George and remote responsibilities.

Employees will have access to state-of-the-art analytical instrumentation and a supportive, research-driven work environment.

Our client is committed to fostering innovation and scientific excellence, providing a rewarding career path in the pharmaceutical sector.

You will contribute to the development of vital medicines, working with a dedicated team.