Senior Analytical Chemist - Pharmaceutical Quality Control

Placements24; Gqeberha; Hybrid; ZAR 700,000 - 900,000; Full time

Benefits offered by this job

Health insurance

Retirement plan

Job summary

Placements24 in Port Elizabeth is seeking a Senior Analytical Chemist to strengthen our client's Quality Control team. The role focuses on developing, validating, and applying analytical methods for raw materials, in-process samples and finished products in a GLP/GMP environment.

You will lead method transfer, perform routine testing using HPLC, GC and UV-Vis, investigate OOS, maintain instruments, and mentor junior chemists in a hybrid on-site/remote setting.

Qualifications

• Bachelor's or Master's degree in Chemistry or related field.
• Minimum of 5 years in pharmaceutical analytical chemistry, with a strong focus on Quality Control.
• Experience with HPLC/GC and method validation per ICH.

Responsibilities

• Develop, validate, and transfer analytical methods for pharmaceutical compounds.
• Perform routine testing of raw materials, intermediates, and finished products.
• Investigate out-of-specification (OOS) results and deviations, implementing CAPAs.
• Maintain and calibrate analytical instrumentation.
• Prepare and review analytical method validation reports, stability protocols, and batch release documentation.
• Ensure compliance with GLP and GMP guidelines.
• Collaborate with cross-functional teams including R&D, production, and regulatory affairs.
• Train and mentor junior analytical chemists.

Skills

HPLC

GC

Analytical testing

Quality control

Method development

ICH guidelines

GLP/GMP

Education

Bachelor's degree in Chemistry

Master's degree in Analytical Chemistry

Tools

LIMS

Job description

About the Role

Our client, a rapidly growing pharmaceutical company, is seeking a highly skilled Senior Analytical Chemist to join their Quality Control department. This Hybrid role is based in the scenic city of Port Elizabeth, Eastern Cape, ZA . You will play a crucial role in ensuring the quality, safety, and efficacy of pharmaceutical products through rigorous analytical testing. The position involves the development, validation, and application of advanced analytical methods for raw materials, in-process samples, and finished products. You will work within a GLP/GMP-compliant laboratory environment, collaborating with regulatory affairs and product development teams. This is an excellent opportunity for an experienced analytical chemist to contribute to high-stakes product quality assurance in a supportive and dynamic setting.

Key Responsibilities

• Develop, validate, and transfer analytical methods for pharmaceutical compounds using techniques such as HPLC, GC, UV-Vis, KF, and dissolution testing.
• Perform routine testing of raw materials, intermediates, and finished products according to established specifications and procedures.
• Investigate out-of-specification (OOS) results and deviations, implementing corrective and preventive actions (CAPAs).
• Maintain and calibrate analytical instrumentation, ensuring optimal performance.
• Prepare and review analytical method validation reports, stability protocols, and batch release documentation.
• Ensure compliance with Good Laboratory Practice (GLP) and Good Manufacturing Practice (GMP) guidelines.
• Collaborate with cross-functional teams, including R&D, production, and regulatory affairs.
• Train and mentor junior analytical chemists.

Requirements

• Bachelor's or Master's degree in Chemistry, Analytical Chemistry, Pharmaceutical Sciences, or a related field.
• Minimum of 5 years of experience in pharmaceutical analytical chemistry, with a strong focus on Quality Control.
• Proficiency in various analytical techniques, particularly HPLC and GC.
• Experience with method development and validation according to ICH guidelines.
• Solid understanding of GMP and GLP regulations.
• Experience with laboratory information management systems (LIMS) is a plus.
• Excellent attention to detail, problem-solving abilities, and scientific rigor.
• Strong written and verbal communication skills.
• Ability to work effectively in a hybrid environment, balancing on-site and remote responsibilities.

Benefits

• Our client offers a competitive salary, comprehensive health insurance, and retirement benefits.
• Opportunities for professional development, including further training and conference attendance, are readily available.
• Employees enjoy a supportive work culture and the chance to contribute to life-changing pharmaceutical products.
• The hybrid work model provides a good balance between in-office collaboration and remote flexibility in Port Elizabeth, Eastern Cape, ZA .