Senior Analytical Chemist – Pharma Development & Impurity Profiling

Placements24; Vereeniging; On-site; ZAR 900,000 - 1,300,000; Full time

Benefits offered by this job

Medical aid

Retirement fund

Life insurance

Performance bonuses

Annual leave

Advanced training programs

Job summary

Placements24 is seeking a Senior Pharmaceutical Chemist specializing in Analytical Development for our Vereeniging facility to lead the development, validation, and implementation of methods ensuring product quality.

The role requires extensive experience in pharmaceutical analysis and a track record of solving complex analytical challenges, with collaboration across R&D, manufacturing, and regulatory affairs in a fast-paced environment.

Qualifications

• Ph.D. or Master’s in Analytical, Organic, Pharmaceutical Chemistry or related field.
• Minimum 6 years of analytical method development and validation in pharma.
• Expertise with HPLC/UPLC and GC.
• Strong knowledge of ICH guidelines and GMP regulatory submissions.
• Experience with impurity profiling and stability testing.
• Excellent scientific writing and verbal communication abilities.

Responsibilities

• Develop and validate analytical methods for raw materials, in-process controls, and finished products (HPLC, GC, LC-MS, GC-MS, ICP-MS, spectroscopy).
• Transfer methods to QC labs and provide ongoing support.
• Troubleshoot and optimize analytical methods for efficiency and robustness.
• Characterize impurities and degradation products of pharmaceutical compounds.
• Conduct stability studies and analyze data.
• Prepare validation protocols and reports per ICH and regulatory guidelines.
• Collaborate with R&D, manufacturing, and regulatory affairs.
• Maintain lab equipment and ensure GLP/GMP compliance.
• Contribute to regulatory submissions with analytical data.
• Mentor junior analytical chemists.

Skills

Analytical chemistry

HPLC/UPLC

GC

ICH & GMP knowledge

Impurity profiling

Stability testing

Scientific writing

Project management

Data analysis software

LIMS familiarity

Education

Ph.D. or Master’s in Analytical/Organic/Pharmaceutical Chemistry

Tools

LIMS

Data analysis software

Job description

Placements24 is seeking a Senior Pharmaceutical Chemist specializing in Analytical Development for our Vereeniging facility to lead the development, validation, and implementation of methods ensuring product quality.

The role requires extensive experience in pharmaceutical analysis and a track record of solving complex analytical challenges, with collaboration across R&D, manufacturing, and regulatory affairs in a fast-paced environment.