Remote Senior Structural Biologist - Cryo-EM Specialist

Placements24; Munrohoek; Hybrid; ZAR 1,800,000 - 2,400,000; Full time

Benefits offered by this job

Stock options

Bonuses

Health & dental insurance

Retirement plan

Paid time off

Conference attendance

Home office stipend

Job summary

Placements24 is seeking a Senior Structural Biologist with Cryo‑EM expertise to join a fully remote team focused on pharmaceutical structure determination. You will lead experimental design, data acquisition, and model building for high‑resolution structures of challenging protein targets relevant to drug discovery.

The role requires a Ph.D. with extensive post‑doctoral Cryo‑EM experience, hands‑on use of Krios/Talos and software like RELION, cisTEM, and cryoSPARC, and strong collaboration in

Qualifications

• Ph.D. required in Structural Biology or related field.
• Minimum 6 years post‑doctoral Cryo‑EM experience.
• Proven track record with high‑resolution protein structures via Cryo‑EM.

Responsibilities

• Design and execute Cryo-EM experiments to determine structures of protein targets.
• Prepare samples and perform grid screening, data collection, processing.
• Build and refine atomic models into electron density maps.
• Collaborate with chemists/biologists for structure‑based drug design.
• Publish findings and contribute to IP through patents.

Education

Ph.D. in Structural Biology

Tools

Cryo-EM hardware (Krios/Talos)

RELION

cisTEM

cryoSPARC

Job description

Placements24 is seeking a Senior Structural Biologist with Cryo‑EM expertise to join a fully remote team focused on pharmaceutical structure determination. You will lead experimental design, data acquisition, and model building for high‑resolution structures of challenging protein targets relevant to drug discovery.

The role requires a Ph.D. with extensive post‑doctoral Cryo‑EM experience, hands‑on use of Krios/Talos and software like RELION, cisTEM, and cryoSPARC, and strong collaboration in