Remote Pharmaceutical Process Engineer — Scale-Up & Validation

Placements24; Polokwane; Hybrid; ZAR 900,000 - 1,500,000; Full time

Benefits offered by this job

Health insurance

Retirement plan contributions

Paid time off

Remote work flexibility

Professional development opportunities

Job summary

Placements24 is seeking a Process Development Engineer to join a global pharmaceutical company in a fully remote role across South Africa. You will design, develop and optimize manufacturing processes for novel drug products, ensuring compliance with cGMP and regulatory guidelines while enabling scalable production.

You will collaborate with R&D, QA and Manufacturing teams, conduct process validation, develop control strategies and document batch records, SOPs and validation protocols,

Qualifications

• Bachelor's or Master's degree in Chemical Engineering, Pharmaceutical Engineering, or a related discipline.
• Minimum of 5 years of experience in pharmaceutical process development and manufacturing.
• Strong understanding of unit operations in pharmaceutical manufacturing (granulation, drying, milling, tablet compression, sterile filling).
• Proficiency in process validation principles and SPC.
• Experience with GMP and regulatory requirements.
• Excellent problem-solving, analytical and communication skills.
• Ability to work remotely and manage multiple priorities.
• Experience with process simulation software (Aspen Plus, gPROMS) is a significant advantage.
• Knowledge of QbD principles is highly desirable.

Responsibilities

• Design, develop, and optimize pharmaceutical manufacturing processes, focusing on efficiency, scalability, and cost-effectiveness.
• Conduct process validation studies and develop robust control strategies.
• Troubleshoot manufacturing issues and implement CAPAs.
• Collaborate with R&D, Quality Assurance, and Manufacturing teams to ensure seamless process transfer and scale-up.
• Develop process documentation, including batch records, SOPs, and validation protocols.
• Utilize process modeling and simulation tools to predict and optimize process performance.
• Stay current with emerging technologies and best practices in pharmaceutical process engineering.
• Ensure all activities comply with cGMP, FDA, EMA, and other relevant regulatory guidelines.
• Evaluate and select appropriate manufacturing equipment and technologies.
• Contribute to the development of intellectual property through process innovation.

Skills

Problem-solving

Analytical thinking

Critical thinking

Remote collaboration

Education

Bachelor's or Master's degree in Chemical Engineering, Pharmaceutical Engineering, or related field

Tools

Aspen Plus

gPROMS

Process modeling tools

Job description

Placements24 is seeking a Process Development Engineer to join a global pharmaceutical company in a fully remote role across South Africa. You will design, develop and optimize manufacturing processes for novel drug products, ensuring compliance with cGMP and regulatory guidelines while enabling scalable production.

You will collaborate with R&D, QA and Manufacturing teams, conduct process validation, develop control strategies and document batch records, SOPs and validation protocols,