Formulation Scientist - Oral Dosage Forms

Placements24; Mossel Bay; On-site; ZAR 900,000 - 1,500,000; Full time

Benefits offered by this job

Relocation assistance

Competitive salary

R&D focused environment

Job summary

Placements24 in Mossel Bay is seeking a highly skilled Formulation Scientist specializing in oral dosage forms to join its R&D team. You will lead pre-formulation studies, formulation development, and scale-up activities for solid dosage forms.

The ideal candidate has a Master’s or Ph.D. in Pharmaceutical Sciences or related field and 5+ years of hands-on experience with drug delivery systems, excipients, and DoE. Collaboration with analytical chemists and regulatory affairs is essential.

Qualifications

• Master's or Ph.D. in Pharmaceutical Sciences, Pharmaceutics, Chemistry, or a related discipline.
• 5+ years of hands-on experience in pharmaceutical formulation development, with a strong focus on oral dosage forms.
• In-depth knowledge of drug delivery systems, polymer science, and pharmaceutical excipients.
• Experience with formulation and manufacturing equipment (e.g., tablet presses, capsule fillers, granulators).
• Proficiency in statistical analysis and design of experiments (DoE) principles.
• Excellent scientific curiosity, problem-solving abilities, and strong communication skills.

Responsibilities

• Design and develop novel formulations for various oral dosage forms (tablets, capsules, powders).
• Conduct pre-formulation studies to characterize drug substances and select appropriate excipients.
• Optimize formulation composition and manufacturing processes to achieve desired drug release profiles and stability.
• Perform formulation development, including experimental design (DoE), screening, and optimization.
• Scale up laboratory formulations to pilot and commercial manufacturing processes.
• Collaborate with analytical chemists, process engineers, and regulatory affairs to ensure successful product development and regulatory submissions.

Skills

Formulation development

Oral dosage forms

DoE principles

Communication skills

Analytical thinking

Education

Master's or Ph.D. in Pharmaceutical Sciences / Pharmaceutics / Chemistry

Tools

Tablet presses

Capsule fillers

Granulators

Job description

About the Role

Our client is seeking an innovative and detail-oriented Formulation Scientist specializing in oral dosage forms to join their dedicated R&D team in Mossel Bay . This role is at the forefront of developing new and improved solid oral dosage forms, including tablets and capsules. You will be responsible for pre-formulation studies, formulation development, process optimization, and scale-up activities. The ideal candidate will bring a strong understanding of pharmaceutical excipients, drug delivery technologies, and a passion for bringing new therapies to market. You will be instrumental in shaping the company's product pipeline and contributing to scientific advancements within the pharmaceutical industry.

Key Responsibilities

• Design and develop novel formulations for various oral dosage forms (tablets, capsules, powders).
• Conduct pre-formulation studies to characterize drug substances and select appropriate excipients.
• Optimize formulation composition and manufacturing processes to achieve desired drug release profiles and stability.
• Perform formulation development, including experimental design (DoE), screening, and optimization.
• Scale up laboratory formulations to pilot and commercial manufacturing processes.
• Collaborate with analytical chemists, process engineers, and regulatory affairs to ensure successful product development and regulatory submissions.

Requirements

• Master's or Ph.D. in Pharmaceutical Sciences, Pharmaceutics, Chemistry, or a related discipline.
• 5+ years of hands-on experience in pharmaceutical formulation development, with a strong focus on oral dosage forms.
• In-depth knowledge of drug delivery systems , polymer science, and pharmaceutical excipients.
• Experience with formulation and manufacturing equipment (e.g., tablet presses, capsule fillers, granulators).
• Proficiency in statistical analysis and design of experiments (DoE) principles.
• Excellent scientific curiosity, problem-solving abilities, and strong communication skills.

Benefits

• Highly competitive salary and comprehensive benefits package.
• Opportunity to work on cutting-edge pharmaceutical research projects.
• Generous allowance for professional development and scientific conferences.
• Collaborative and innovative research environment.
• Relocation assistance may be available for qualified candidates.