Biologics Process Development Engineer — Hybrid Role

Placements24

Benoni

Hybrid

ZAR 900,000 - 1,500,000

Full time

2 days ago

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Benefits offered by this job

Hybrid work arrangement

Job summary

Placements24 seeks an experienced Senior Process Development Engineer to join our Benoni team, focusing on scale-up and optimization of biologics manufacturing processes for therapeutic proteins and antibodies.

You will translate lab-scale processes to pilot and commercial scales, develop upstream and downstream methods, and collaborate with manufacturing, QA, and regulatory teams. A strong biochemical engineering background with cell culture or fermentation experience is essential.

Qualifications

MSc or PhD in Chemical Engineering, Biochemical Engineering, Biotechnology, or a related field.
Minimum of 5 years of experience in process development for biologics manufacturing.
Hands-on experience with mammalian cell culture or microbial fermentation.
Proficiency in downstream processing techniques, including chromatography and filtration.
Strong understanding of process modeling, statistical analysis, and QbD principles.
Excellent problem-solving skills and ability to work in a multidisciplinary team.

Responsibilities

Develop, optimize, and scale-up upstream (cell culture/fermentation) and downstream (chromatography/filtration) processes for biologics.
Design and execute experiments to improve process performance, robustness, and yield.
Troubleshoot process deviations and implement solutions to ensure product quality and manufacturing continuity.
Author process development reports, validation protocols, and technology transfer documents.
Collaborate with manufacturing, QA, and regulatory teams to ensure successful process implementation.
Stay current with emerging technologies and best practices in biopharmaceutical process development.