Upstream Bioprocess Scientist — Scale-Up & QbD Expert

Elanco; Indianapolis (IN); Hybrid; USD 110,000 - 150,000; Full time

Benefits offered by this job

Relocation packages

Shutdowns (mid-summer & year-end)

Parental leave (8 weeks)

Employee Resource Groups

Annual bonus offering

Flexible work arrangements

401K matching (up to 6%)

LI-JC1

Job summary

Elanco is seeking an Upstream Bioprocess Development Scientist to advance upstream processes for its Biotherapeutic portfolio. You will work across scales from flasks to bioreactors, collaborating with Downstream, Formulations, and Analytical teams to drive innovation and quality.

The role emphasizes design of experiments, safety, data integrity, and preparation of regulatory‑relevant documentation. Travel is 10% with hybrid work locations globally, including Indianapolis.

Qualifications

• Bachelor’s Degree in Biology, Molecular Biology, Microbiology, or related scientific discipline (or equivalent level of experience).
• Minimum of five years of hands‑on experience working with mammalian cell lines or similar.

Responsibilities

• Conceive, plan, schedule, and execute laboratory experiments from shake flasks to bioreactors for the Large Molecule portfolio.
• Apply Quality by Design (QbD) and Design of Experiments (DOE) to optimize product quality and yield.
• Maintain laboratory infrastructure and safety protocols for housekeeping and equipment maintenance.
• Analyze and interpret complex datasets to inform experimental design and communicate findings to cross‑functional teams.
• Author technical reports, SOPs, and contribute to regulatory submissions and knowledge transfer.

Skills

Mammalian cell culture

Data interpretation

Collaborative communication

Education

Bachelor’s Degree in Biology or related

5+ years mammalian cell line experience

Tools

QbD/DOE methods

Job description

Elanco is seeking an Upstream Bioprocess Development Scientist to advance upstream processes for its Biotherapeutic portfolio. You will work across scales from flasks to bioreactors, collaborating with Downstream, Formulations, and Analytical teams to drive innovation and quality.

The role emphasizes design of experiments, safety, data integrity, and preparation of regulatory‑relevant documentation. Travel is 10% with hybrid work locations globally, including Indianapolis.