Translational Neuroscience Postdoc In Vivo Neurodegeneration

MSD Malaysia; West Point (PA); On-site; USD 82,000 - 92,000; Full time

Job summary

Merck & Co., Inc. in the United States is seeking a Postdoctoral Fellow in Translational Neuroscience to advance therapies for neurodegenerative diseases.

The role focuses on preclinical and translational research using rodent models, translational biomarkers, and in vivo imaging. You will design and execute experiments, generate mechanistic insights, and collaborate across neuroscience, imaging, pharmacology, and data science teams.

Qualifications

• PhD in Neuroscience, Pharmacology, Biomedical Sciences, or related field required.
• Strong hands-on experience with rodent models and translational imaging technologies.

Responsibilities

• Design and conduct preclinical studies using rodent models of neurodegenerative diseases.
• Perform hands-on in vivo experiments, including dosing, tissue collection, and downstream biomarker analyses.
• Apply biochemical and molecular techniques, including ELISA, Meso Scale Discovery, immunohistochemistry, and ultrasensitive biomarker assays.
• Develop and utilize in vivo MRI methods to evaluate neuroinflammation, blood–brain barrier integrity, and other translational endpoints.
• Integrate imaging, fluid biomarker, and pharmacological datasets to uncover disease mechanisms and therapeutic responses.
• Collaborate with scientists across neuroscience, translational imaging, pharmacology, and data science to generate scientific insights that influence project strategy and decision‑making.
• Present findings through internal presentations, scientific conferences, and peer‑reviewed publications.

Skills

Biomarkers

Data Analysis

DOE

Disease Models

Immunoassays

In Vivo Models

Neurodegeneration

Neuroinflammation

Scientific Research

Statistical Analysis

Education

PhD in Neuroscience, Pharmacology, Biomedical Sciences, or related

Tools

MRI

ELISA

Meso Scale Discovery

Immunohistochemistry

Quanterix assays

GraphPad Prism

HALO

MATLAB

Python

Job description

Merck & Co., Inc. in the United States is seeking a Postdoctoral Fellow in Translational Neuroscience to advance therapies for neurodegenerative diseases.

The role focuses on preclinical and translational research using rodent models, translational biomarkers, and in vivo imaging. You will design and execute experiments, generate mechanistic insights, and collaborate across neuroscience, imaging, pharmacology, and data science teams.