Translational Neuroscience Principal Scientist (Hybrid)

MSD; Rahway (NJ); Hybrid; USD 280,000 - 379,000; Full time

Benefits offered by this job

Medical, dental, vision benefits

401(k) retirement benefits

Paid holidays and vacation

Job summary

Merck & Co., Inc. in Rahway, NJ is seeking a physician-scientist to join Translational Medicine as Principal Scientist (Clinical Director) in Early Clinical Development.

The role focuses on neurology/psychiatry targets, with responsibilities across target validation, preclinical-to-clinical transition, and biomarker-driven studies. The successful candidate will lead cross-functional teams, design early phase studies, and contribute to regulatory filings.

Qualifications

• MD or MD/PhD required with clinical medicine training.
• Proven track record in biomedical research and collaboration across therapeutic areas.
• Strong writing, presentation, and interpersonal skills.

Responsibilities

• Lead early clinical development strategy from preclinical to Phase 2.
• Provide clinical pharmacology input across all phases (I–IV).
• Collaborate with cross-functional teams and external partners.
• Develop biomarker strategies and support regulatory filings.

Skills

Biomedical Research

Clinical Development

Clinical Medicine

Clinical Research

Clinical Trial Planning

Cross-Functional Teamwork

Neuroscience Research

Neurologic Disorders

Translational Research

Education

MD or MD/PhD

Job description

Merck & Co., Inc. in Rahway, NJ is seeking a physician-scientist to join Translational Medicine as Principal Scientist (Clinical Director) in Early Clinical Development.

The role focuses on neurology/psychiatry targets, with responsibilities across target validation, preclinical-to-clinical transition, and biomarker-driven studies. The successful candidate will lead cross-functional teams, design early phase studies, and contribute to regulatory filings.