Supply Planning Lead, CVRM

Genentech; Holly Springs (MS); On-site; USD 120,000 - 160,000; Full time

Job summary

Roche/Genentech seeks a seasoned Supply Planning Lead at its Holly Springs site to drive the site’s supply planning, S&OP rhythm, and KPI governance. You will lead a high-performing team, align demand with global supply strategies, and ensure finished goods availability while optimizing working capital.

You will collaborate with production, purchasing, and logistics to translate demand into actionable schedules, manage inventory health, and guide continuous improvement initiatives in a

Qualifications

• Lead and develop the site supply planning team and standardize the S&OP/IBP process.
• Define and monitor site KPIs (OTIF, Schedule Attainment, Plan Adherence).
• Oversee Master Data governance (lead times, safety stock, lot sizes) in SAP.
• Collaborate across Demand, Site Execution, and Global supply chain strategies.

Responsibilities

• Lead and manage the site supply planning team for end-to-end execution.
• Establish robust governance of material planning, import/export, and customs clearance.
• Translate demand plans into Master Production Schedules (MPS) with Production and Purchasing teams.
• Drive inventory optimization and minimize write-offs while maintaining service levels.
• Lead continuous improvement and cross-functional collaboration with global networks.

Skills

Team leadership

S&OP/IBP process

RCCP capacity planning

Supply chain analytics

Data integrity (Master Data)

Tools

SAP

Job description

Welcome to Holly Springs, North Carolina- home to Roche/Genentech's largest-ever investment: a $2B greenfield start-up where next-generation technology, high-performing teams, and Operational Excellence converge to create the global standard for high-volume, highly-efficient Drug Product manufacturing.

The facility's core is defined by innovation-leveraging advanced automation, robotics, digital tools, real-time data analytics, and simple, streamlined processes to produce the highest quality medicines. This plant meets today's demand for CVRM (Cardiovascular, Renal, and Metabolism) medicines and is scalable to grow with the portfolio, which focuses on next-generation metabolic medicines specifically targeting the global obesity epidemic and Type 2 diabetes. This is a fast-paced, entrepreneurial environment with a high level of accountability, targeted for commercial launch in 2028.

The Opportunity

We are seeking an experienced and strategic Supply Planning Lead to manage and inspire a high-performing supply planning team, driving site operational planning, inventory optimization, and alignment with global business objectives at our Holly Springs site. In this role, you will lead the site supply planning organization, guide the local Sales and Operations Planning (S&OP) rhythm, and serve as a key people leader linking commercial demand, site execution, and global supply chain strategies.

What You'll Do

Phase 1: Start-up (Process & Capability Building)

• Team Capability & S&OP Framework: Recruit, onboard, and develop the site supply planning team; establish and standardize the site S&OP/IBP process to align site capacity with long-term commercial demand forecasts.
• Leadership & Pre-S&OP Facilitation: Direct and facilitate the site Pre-Supply Planning Meeting, coaching team members to evaluate rough-cut capacity planning (RCCP), identify capacity bottlenecks, and present dynamic resolution options.
• Define Metrics & Performance: Define and standardize Supply Chain KPIs, including Schedule Attainment, Plan Adherence, OTIF (On-Time In-Full), Inventory Turn/Health, and Supply Plan Accuracy.
• People Management & Customer Service: Lead and direct the batch disposition and customer service team to ensure transparent inventory availability, manage risk-of-supply communications, and resolve order fulfillment escalations.
• Data Integrity: Oversee supply planning Master Data process development, standardization, and governance in SAP (e.g., lead times, safety stock levels, lot sizes, yield rates, min/max thresholds, and planning BOMs) to ensure high planning system accuracy.
• Inventory Optimization: Develop a process and partnership to manage finished goods and work-in-progress (WIP) inventory levels to achieve working capital targets while maintaining targeted customer service levels.

Phase 2: Routine Operations (Ongoing Execution & Management)

• Team Leadership & Operational Service: Lead and manage a high-performing supply planning team to maintain high-caliber end-to-end supply chain execution, fostering cross-functional collaboration to ensure product availability and optimal stock levels.
• Governance & Policy Compliance: Establish robust oversight and enforce strict adherence to organizational supply chain policies and operating guidelines across material planning, import/export, and required customs clearance for incoming/outgoing materials.
• Operations Leadership & Monitoring: Direct daily supply chain operations and customer order processing, driving performance management across OTIF metrics while supporting team members in resolving complex supply escalations.
• Production & Purchasing Integration: Direct the translation of the consensus demand plan into actionable master production schedules (MPS), collaborating closely with site Production Schedulers and Purchasing teams to manage component availability and shop-floor constraints.
• Inventory & Bottleneck Mitigation: Proactively manage inventory levels to prevent write-offs from expiry, mitigate supply bottlenecks in coordination with Product Managers, and drive the local S&OP process.
• Continuous Improvement: Identify and execute process improvement initiatives to streamline operations, lower costs, and secure stakeholder alignment across internal workflows and vendor networks.
• Cross-Functional & Global Collaboration: Partner across the site and with a global/regional supply chain network to resolve complex operational challenges effectively.
• People Leadership & Resource Management: Directly manage, mentor, and evaluate supply planning staff, overseeing performance