Supervisor Manufacturing

WuXi AppTec; Philadelphia (Philadelphia County); On-site; USD 60,000 - 100,000; Full time

Job summary

An established industry player is seeking a Supervisor for Manufacturing to lead a dynamic team in the production of cutting-edge Cell & Gene Therapy products. This role is pivotal in ensuring compliance with Good Manufacturing Practices while overseeing aseptic operations and material preparation. The ideal candidate will bring a wealth of experience, strong leadership skills, and a commitment to continuous improvement. Join a forward-thinking organization that values diversity and inclusion, and help drive innovation in the biotechnology sector.

Qualifications

• 5+ years of relevant experience with at least 2 years in a leadership role.
• Strong knowledge of GMP and experience in cell and gene therapy manufacturing.

Responsibilities

• Oversee and manage performance in aseptic operations and material preparation.
• Ensure compliance with regulatory requirements and GMP standards.
• Train employees on batch records, SOPs, and equipment.

Skills

Lean/Six Sigma knowledge

GMP knowledge

Basic engineering skills

Excellent communication skills

Microsoft Office proficiency

Education

HS Diploma or equivalent

BS/BA in Science

Tools

LIMS

Job description

Job Description: Supervisor Manufacturing at WuXi AppTec

Join to apply for the Supervisor Manufacturing role at WuXi AppTec.

This role involves providing leadership in the manufacture of Master and Working Cell Banks, supporting the production of Cell & Gene Therapy products, and final product fills in compliance with current Good Manufacturing Practices (cGMPs). The shift is Monday to Friday, during core business hours.

Responsibilities

1. Oversee, train, coach, mentor, and manage performance in aseptic operations, solution and material preparation, analysis, and facility start-up engineering and mechanical tasks.
2. Teach and coach on equipment operations, troubleshooting, and ancillary support functions.
3. Drive sourcing and procurement of equipment.
4. Review and approve solution and material preparation results; resolve issues.
5. Review protocols and technical transfer documents.
6. Apply GMP concepts, suggest process improvements during technical transfer phases.
7. Execute validation activities, forecast, and perform material procurement.
8. Utilize and act as SME or super user for support systems like LIMS.
9. Lead or participate in system design or improvements.
10. Ensure team training on operations such as media prep, thawing, passage, and harvesting.
11. Interpret data, identify process gaps, and implement improvements.
12. Maintain documentation, review data, and communicate findings.
13. Ensure compliance with regulatory requirements and GMP standards.
14. Train employees on batch records, SOPs, equipment, and systems.
15. Author and review technical documents, lead continuous improvement initiatives.
16. Manage scheduling, staffing, and team performance.
17. Support cross-functional teams and communicate organizational updates.

Qualifications

• HS Diploma or equivalent required; BS/BA in Science preferred.
• 5+ years relevant experience, with at least 2 years in a leadership role.

Knowledge, Skills, and Abilities

• Lean/Six Sigma knowledge preferred.
• Strong arithmetic, GMP knowledge, and basic engineering skills.
• Experience in cell and gene therapy manufacturing.
• Excellent communication skills in English; proficiency in Microsoft Office.

We are an Equal Opportunity Employer, committed to diversity and inclusion.